Prof. Dr. Adrian Press, Dr. Philipp Ernst, Wanling Foo
Lectures: every Monday 10.00 - 12.00 (see below), starting on Oct 18th.
18.10.: SR 3 Bachstr. 18 (building 6; when you enter the area through the metal door from the Carl-Zeiss-Str. then you will see on the left a yellow building. The seminar room is almost at the end.)
all other dates: SR 12 Forschungszentrum Lobeda (FZL Building, Scientific Center; Lobeda University Hospital)
Essential to an efficient therapy of many diseases is a precise diagnosis and a selective application of potent therapeutic agents. To this aim imaging methods have been improved, and strategies for targeted delivery and localized activation of therapeutic agents have been developped.
Theranostic approaches try to combine diagnostic and therapeutic techniques by synthesizing carrier systems capable of specific targeting and carrying imaging and therapeutic agents for accurate diagnosis and controlled release. This course introduces the student into current techniques and therapeutic applications.
Topics covered in the course are:
Theranostics: Definition and Introduction
Dyes, fluorophores and nanomaterials for light-based diagnostic applications
Photodynamic therapy, photosensitizers
Design principles of carrier structures
Diagnostic and therapeutic agents
Activate knowledge of the participants and engage in a discussion and learing about the terminology
When do we treat?
Understanding the dilemma of Theranostics and end-of-life descisions. Meet clinical needs.
Nanomedicine I - Introduction
Engaging in the translational questions of nanomedicine. Which materials are available? How does it work? How can Nanomedicine be superior to conventional pharmacology?
Nanomedicine II - The cellular and physiologic basis
Learn about how nanocarrier interact with the body? What need to be considered when designing drug-delivery systems and how may a "tissue-specific" drug delivery be acchieved?
Nanomedicine III - Cellular Basics
Molecular Mechanism of Nanomedicine: endocytosis, inflamamtory reaction, mechanism of immune reaction
Nanomedicine IV - Nanotheranostics
Why there is so little nanomedicine yet? How can nanomedicine become more successful? Bottlenecks and novel Photonic solutions.
Theranostic Antibiotics - clinical need, microbiological background
Clinical Need? How do antibiotics kill bacteria? What is "resistance"? What are current clinical limitations?
Theranostic Antibiotics - diagnosics
Understanding methods to identify bacteria and resisteance using biophotonics.