Module A1.4 - Human Biology I
Coordinator
Prof. Dr. Christoph Biskup
Lecturers
- Biomolecular Photonics Group: Prof. Dr. Christoph Biskup, PD. Dr. Christian Melle
- Institute of Physiology I: Prof. Dr. Hans-Georg Schaible, PD Dr. Andrea Ebersberger
- Experimental Nephrology Group: Prof. Dr. Ralf Mrowka
Components of the module
- Virtual lectures: Please, follow the links on the download page to view the lectures.
- Exercise questions for self study.
- Seminars: Online seminars/tutorials to discuss remaining questions. Please, follow the links below to participate in the meetings.
Additional help
To help you in learning Human Biology the following tools can be borrowed/obtained:
- Molecular models: A set of color coded atoms such as the one used in the lecture videos can be borrowed from the Biomeolecular Photonics group.
- Virtual microscopy: Login and pwd for the virtual microscope of the Dept. of Anatomy (link)
To get these items, please stop by at the office of Mrs. Noßmann on Fridays between 12.30 and 13.30. To see her, enter the Biochemistry building of the Medical Theoretical Institues (Nonnenplan 4), go to the first floor and select her name from the dial pad to ask her to open the door (or call her by phone: 03641-9396710). Take the hallway to the left, pass the fire protection door, follow the hallway until you see the sign ("Koordinatirbüro"), turn left, and pass the fire protection door at half of the length of the hallway. Mrs. Nossmann's office is almost at the end of the hallway at the left side.
Requirements to complete this module
- Self study of the recommended textbook chapters. For this course we will use OpenStax Anatomy & Physiology (2017). The textbook is available free of charge at https://openstax.org/details/books/anatomy-and-physiology. A pdf of the book can be downloaded here.
- Self study of the online lectures
- Regular work on the exercises
- Successful participation in the written exam
Exam
Please note: date, time and location might be still subject to changes.
- Date: 25.03.2021
- Time: 10.00 a.m.
- Location: Big lecture hall of the theoretical medical institutes
Time table and overview of the individual lectures
| Unit | Lecturer | Subject and content | Links |
|
Week 1 1 |
Biskup |
Zoom meeting Introduction into Human Biology
|
Link to join the meeting: See the download page for a copy of the lecture slides |
| 2 | Biskup |
Introduction into medical terminology |
See the download page for additional materials |
| 3 | Biskup |
Organization of the cell
|
See the download page for additional materials |
|
Week 2 4 |
Biskup |
Zoom meeting Discussion of questions concerning the topics of last week
|
Link to join the meeting: |
| 5 | Biskup |
Morphology and classification of tissues
|
See the download page for additional materials |
| 6 | Biskup |
The integumentary sytem
|
See the download page for additional materials |
| Week 3 Monday 16.11.2020 9.30 a.m. |
Biskup |
Zoom meeting Discussion of questions concerning the topics of week #2 Microscopic anatomy
|
Link to join the meeting: See the download page for additional materials |
|
7 |
Biskup |
Biomolecules I
See also the Chemistry Precourse for more details |
See the download page for a video lecture |
| 8 | Biskup |
Biomolecules II
See the Chemistry Precourse for more details. |
See the download page for slides and review questions |
| 9 | Biskup |
Biomolecules III
See the Chemistry Precourse for more details. |
See the download page for slides and review questions |
| 10 | Biskup |
Biomolecules IV
|
See the download page for slides and review questions |
|
Week 4 |
Biskup |
Zoom meeting Discussion of questions concerning the topics of week #3 |
Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 |
|
11 |
Melle | Chromosome structure | See the download page for a video lecture |
| 12 | Melle | DNA replication | See the download page for a video lecture |
| 13 | Melle |
Cell cycle, cell reproduction
|
See the download page for a video lecture |
| 14 | Melle | Mitosis, meiosis, recombination |
See the download page for a video lecture |
|
Week 5 |
Melle |
Zoom meeting Discussion of questions concerning the topics of week #4 |
Link to join the meeting: |
|
15 |
Melle |
Transcription & translation
|
See the download page for a video lecture |
| 16 | Melle | DNA damage
|
See the download page for a video lecture |
| 17 | Mrowka | Molecular cloning
|
See the download page for a video lecture |
|
Friday |
Melle/ Mrowka |
Zoom meeting Discussion of questions concerning the topics of week #5 |
Link to join the meeting: |
|
Week 6 18 |
Biskup |
Thermodynamic principles
|
See the download page for slides |
| 19 |
Biskup |
Enzymes, enzyme kinetics
|
See the download page for slides |
|
20 |
Melle |
Metabolism I
|
See the download page for a video lecture |
| 21 | Melle |
Metabolism II
|
See the download page for a video lecture |
| 23 | Melle |
Metabolism III
|
See the download page for a video lecture |
| Friday 18.12.2020 11.00 a.m. |
Biskup / |
Zoom meeting Discussion of questions concerning the topics of last week |
Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 |
|
Week 7 24 |
Mrowka |
Signal transduction I
|
See the download page for a video lecture |
| 25 | Mrowka |
Signal transduction II
|
|
| 26 | Mrowka |
Signal transduction III
|
|
| Monday 04.01.2021 9.30 a.m. |
Melle/ Mrowka |
Zoom meeting Discussion of questions concerning the topics of week #7 |
Link to join the meeting: https://uni-jena-de.zoom.us/j/91516293773 The passcode is: 215851 |
| Week 8 27 |
Biskup | Membrane Physiology I - Biophysical basics
|
See the download page for lecture video, lecture notes and exercises |
| 28 | Biskup |
Membrane Physiology II - Transport phenomena
|
See the download page for lecture video, lecture notes and exercises |
| 29 | Biskup |
Membrane Physiology III - Excitable tissues
|
See the download page for lecture video, lecture notes and exercises |
| Monday 11.01.2021 9.30 a.m. |
Biskup |
Zoom meeting Discussion of questions concerning the topics of week #8 |
Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 |
| Week 9 30 |
Ebersberger |
Physiology of neurons
|
See the download page for a video lecture |
| 31 | Ebersberger |
Synaptic transmission, the neuromuscular junction
|
See the download page for a video lecture |
| 32 | Ebersberger |
Cellular physiology of the skeletal, cardiac and smooth muscle
|
See the download page for a video lecture |
| Monday 18.01.2021 9.30 a.m. |
Biskup |
Zoom meeting Discussion of questions concerning the topics of week #9 |
Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 |
| Week 10 33 |
Biskup |
Macroscopic anatomy I
|
See the download page for literature, lecture slides and exercises |
| 34 | Biskup |
Macroscopic anatomy II
|
See the download page for literature, lecture slides and exercises |
| 35 | Biskup |
Macroscopic anatomy III
|
See the download page for literature, lecture slides and exercises |
| Monday 25.01.2021 9.30 a.m. |
Biskup |
Zoom meeting Discussion of questions concerning the topics of week #10 |
Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 |
|
Week 11 36 |
Schaible |
Organization of the nervous system
|
See the download page for a video lecture |
| 37 | Schaible |
Autonomic nervous system
|
See the download page for links to video lectures |
| Monday 01.02.2021 9.30 a.m. |
Schaible/ |
Zoom meeting Discussion of questions concerning the topics of last week |
Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 |
|
Week 12 38 |
Biskup |
Cardiac physiology I
|
See the download page for lecture video, lecture notes and exercises |
| 39 | Biskup |
Cardiac physiology II
|
See the download page for lecture video, lecture notes and exercises |
|
Week 13 40 |
Biskup |
Cardiac physiology III
|
See the download page for lecture video, lecture notes and exercises |
| 41 | Biskup |
Cardiac physiology IV
|
See the download page for recommended videos and exercises |
| Monday 08.02.2021 9.30 a.m. |
Biskup |
Zoom meeting Discussion of questions concerning the topics of last week |
Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 |
| Monday 15.02.2021 9.30 a.m. |
Biskup |
Zoom meeting Discussion of questions concerning the topics of last week |
Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 |
| Wednesday 03.03.2021 9.30 a.m. |
Biskup |
Additional zoom meeting Review of this semester's topics, discussion of open questions |
Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 |
| Monday 22.03.2021 9.30 a.m. |
Biskup |
Additional zoom meeting Review of this semester's topics, discussion of open questions Note: The zoom meeting has to be postponed to |
Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 |
| Thursday 25.03.2021 10.00 a.m. |
Biskup |
Exam Time: 10.00 a.m - 12.00 am. Location: Big lecture hall of the Medical Theoretical Institutes. Results of the exam can be found here. |
Recommended Textbooks
Anatomy & Physiology
Textbooks
- Donald C. Rizzo
Fundamentals of Anatomy and Physiology, 4th ed.
Cengage Learning, Boston/MA 2015
ISBN: 1285174150
Fundamentals of Anatomy and Physiology is a good introductory text for students who have little or no previous knowledge of anatomy and physiology. However, it does not cover all topics taught in the course in depth. - Elaine N. Marieb, Katja N. Hoehn
Human Anatomy & Physiology, 10th ed.
Perason Education, 2015
ISBN: 1292096971
Human Anatomy and Phyiology gives a good detailed introduction into the human anatomy and physiology. It is basic enough for beginners, but covers a wide range of topics at considerable depth. A good collection of graphics, figures and tables helps elucidating the necessary details of anatomy and physiology. However, many molecular mechanism discussed in the lectures are not covered in this book. - Frederic H. Martini, Judi L. Nath, Edwin F. Bartholomew
Fundamentals of Anatomy and Physiology, 11th ed.
Pearson Education, 2018
ISBN: 1292229861 (Paperback)
Fundamentals of Anatomy and Physiology gives a good introduction into the human anatomy and physiology. Many excellent figures and tables help to elucidate the subjects discussed in the text. However, it does not cover all topics taught in the course in depth. Especially many important molecular and electrophysiological mechanisms are not discussed.
Histology
Textbooks & Atlas
- Anthony L. Mescher
Junqueira's Basic Histology - Text & Atlas, 15th ed.
Mc Graw Hill Education, New York 2018
ISBN: 978-1-260-02617-7
Junqueira's Basic Histology offers concise yet thorough information on human tissue structure and function. An opening chapter reviews the histological techniques that allow understanding of cell and tissue structure. The two following chapters focus on the structural and functional organization of human cells. The next seven chapters cover the four basic tissues that make up our organs: epithelia, connective tissue (and its major sub-types), nervous tissue, and muscle. The remaining chapters explain the organization and functional significance of these tissues in each of the body's organ systems.
A virtual microscope with over 150 slides of all human tissues and organs is available: http://medsci.indiana.edu/junqueira/virtual/junqueira.htm.
Physiology
Textbooks
- Walter F. Boron, Emile L. Boulpaep:
Medical Physiology, 3rd ed.
Elsevier, Oxford 2016.
Medical Physiology is a very comprehensive, very detailed book which covers also the molecular details in unparalleled depth. Complex concepts are presented in a clear, concise, and logically organized format, which facilitates understanding of the topics. However, not all topics, especially in the field of neurophysiology are covered.
- John E. Hall:
Guyton and Hall Textbook of Medical Physiology, 13 th ed.
Elsevier, Oxford 2015.
Guyton and Hall's Textbook of Medical Physiology is the 'classical' textbook used by many students of medicine. The detailed text is complemented by illustrations that summarize key concepts in physiology and pathophysiology. Molecular mechanisms, however, are not covered in detail.
A virtual microscope with over 150 slides of all human tissues and organs is available: http://medsci.indiana.edu/junqueira/virtual/junqueira.htm.
e-books available via the university library (ThuLB)
- Nicholas Sperelakis:
Cell Physiology Source Book, 4th ed.
Elsevier 2011 (Link) - Armin Kurtz, Hans-Christian Pape, Stefan Silbernagl, Anja Bondke Persson, Bernhard Brenner
Physiologie, 7th ed (German)Thieme 2014 (Link)
Cell biology
Textbooks
- Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh , Angelika Amon, Kelsey Martin:
Molecular Cell Biology, 8th edition,
W. H. Freeman, 2016. - Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter:
Molecular Biology of the Cell, 6th Revised edition
Taylor & Francis, 2014.
e-books available via the university library (ThuLB)
Useful Links
Additional resources for microscopic anatomy
On this website you can find links to additional ressources about microscopic anatomy and histologic techniques.
Tutorials about tissue processing and staining
"Leica Pathology Leaders" is a free scientific and educational resource. It offers information ranging from the basics of tissue processing to specific application know-how: Link
Virtual microscope slides
"Virtual microscopes" allow you to study microscopic specimens whenever and whereever you want to if you have access to the internet. The virtual microscope provides the tools to manipulate the specimen by moving it along the x- and y- axis and to change the magnification for a detailed study of the microscopic structures.
For students of the Friedrich-Schiller-University Jena a virtual microscope is available at this link. Use the login and password provided in the course.
Links to other virtual microscopes can be found below: