Module A1.4 - Human Biology I

Coordinator

Prof. Dr. Christoph Biskup

Lecturers

Biomolecular Photonics Group: Prof. Dr. Christoph Biskup, PD. Dr. Christian Melle
Institute of Physiology I: Prof. Dr. Hans-Georg Schaible, PD Dr. Andrea Ebersberger
Experimental Nephrology Group: Prof. Dr. Ralf Mrowka

Components of the module

Virtual lectures: Please, follow the links on the download page or in the moodle room to view the lectures.
In the moodle room also additional material, i.e. exercise sheets and plenty of review questions are availabele.
Seminars: Seminars/tutorials to discuss remaining questions will take place in the lecture hall of the former Institute of Human Genetics. Enter the historic courtyard of the Medical Theoretical Institutes to get access to the lecture hall. A detailed map can be found here.

Additional help

To help you in learning Human Biology the following tools can be borrowed/obtained:

Molecular models: A set of color coded atoms such as the one used in the lecture videos can be borrowed from the Biomeolecular Photonics group.
Virtual microscopy: Virtual microscope of the Dept. of Anatomy (link).

Requirements to complete this module

Self study of the recommended textbook chapters. For this course we will use OpenStax Anatomy & Physiology (2017). The textbook is available free of charge at https://openstax.org/details/books/anatomy-and-physiology. A pdf of the book can be downloaded here.
Self study of the online lectures
Regular work on the exercise sheets to the videos and the questions implemented in moodle
Successful participation in the written exam

Exam

Please note: Like the quizzes, which were available for each unit, most of the actual exam will be performed in moodle. Therefore the exam takes place at one of the computer pools of the core university at the location indicated below. (Note: This is not the computer pool which was used for Image Processing.)

Date: 10.03.2023.
Time: 10.00 a.m. - 12.00 a.m.
Location: Computer Pool - Ernst-Abbe-Platz 8 - 2nd floor - Room 204 (Follow this link for a detailed description)

To be able to login at one of the computers you need to have ready your student login and password of the university computation center (i.e. the login and password you use for Friedolin and Moodle)

Exam results are available here.

Time table and overview of the individual lectures

Unit	Lecturer	Subject and content	Links
Week 1 Unit 1 Monday 17.10.2022 10.15 a.m.	Biskup	Lecture Introduction into Human Biology History Principles Aims of this module, how to survive this module	See the download page for a copy of the lecture slides
Unit 2 Tuesday 18.10.2022 10.15 a.m.	Biskup	Lecture Introduction into medical terminology	See the download page for course materials
Unit 3 Video lecture	Biskup	Organization of the cell Cell morphology Physical structure of the cell Functional organization of the cell: cytoplasm, nucleus, organelles	See the download page for course materials
Friday 21.10.2022 10.15 a.m	Biskup	Seminar Discussion of the test esults Discussion of questions to topics of week #1 Introduction into microscopy The virtual microscope of the Dept. of Anatomy (link)
Week 2 Unit 4 Video lecture	Biskup	Microscopic anatomy Introduction to microscopy Processing and staining of microscopic samples	See the download page for course materials
Unit 5 Video lecture	Biskup	Morphology and classification of tissues Epithelial tissue Connective tissue Muscle tissue Nervous tissue	See the download page for course materials
Unit 6 Video lecture	Biskup	The integumentary sytem Cutaneous membranes: epidermis, dermis Accessory structures: Hair follicles, sebaceous glands, sweat glands, nail	See the download page for course materials
Friday 28.10.2022 10.15 a.m.	Biskup	Seminar Discussion of questions concerning the topics of week #2 The virtual microscope of the Dept. of Anatomy (link)	To prepare for the seminar, please, work through the material of unit #4-#6 which is available on the download page.
Week 3 Unit 7 Video lecture	Biskup	Biomolecules I Proteinogenic amino acids Properties of amino acids "nonstandard" amino acids Protein folding and protein structure See also the Chemistry Precourse for more details	See the download page for a video lecture
Unit 8 Video lecture	Biskup	Biomolecules II Lipids See the Chemistry Precourse for more details.	See the download page for course materials
Friday 04.11.2022 10.15 a.m.	Biskup	Seminar Discussion of questions concerning the topics of week #3	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 4 Unit 9 Video lecture	Biskup	Biomolecules III Carbohydrates See the Chemistry Precourse for more details.	See the download page for course materials
Unit 10 Video lecture	Biskup	Biomolecules IV Nucleic acids, nucleotides, DNA Forces stabilizing the nucleic acid structure DNA replication	See the download page for course materials
Friday 11.11.2022 10.15 a.m.	Biskup	Seminar Discussion of questions concerning the topics of week #4
Week 5 Unit 11 Video lecture	Melle	Chromosome structure	See the download page for the video lecture
Unit 12 Video lecture	Melle	DNA replication	See the download page for the video lecture
Unit 13 Video lecture	Melle	Cell cycle, cell reproduction Cell growth, cell differentiation Cell cycle Cell reproduction Apoptosis	See the download page for the video lecture
Friday 18.11.2022 10.15 a.m.	Melle	Seminar Discussion of questions concerning the topics of week #5	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 6 Unit 14 Video lecture	Melle	Mitosis, meiosis, recombination	See the download page for the video lecture
Unit 15 Video lecture	Melle	Transcription & translation Transcription Translation Regulation of gene expression	See the download page for the video lecture
Friday 25.11.2022 10.15 a.m.	Melle	Seminar Discussion of questions concerning the topics of week #6	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 7 Unit 16 Video lecture	Melle	DNA damage DNA damage signalling DNA repair	See the download page for the video lecture
Unit 17 Video lecture	Mrowka	Molecular cloning recombinant DNA technology chromatographic separations, electrophoresis	See the download page for the video lecture
Friday 02.12.2022 10.15 a.m.	Melle / Mrowka	Seminar Discussion of questions concerning the topics of week #7	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 8 Unit 18 Video lecture	Biskup	Thermodynamic principles Application of the laws of thermodynamics to biochemistry Gibbs free energy, chemical equilibria Enzyme kinetics	See the download page for course materials
Unit 19 Video lecture	Biskup	Enzymes, enzyme kinetics Classification of enzymes Coenzymes Enzyme kinetics, regulation of enzymatic activity	See the download page for course materials
Unit 20 Video lecture	Melle	Metabolism I Glycolysis Glykogen metabolism	See the download page for the video lecture
Friday 09.12.2022 10.15 a.m.	Biskup/ Melle	Seminar Discussion of questions concerning the topics of week #8	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 9 Unit 21 Video lecture	Melle	Metabolism II Citric acid cycle	See the download page for the video lecture
Unit 22 Video lecture	Melle	Metabolism III Oxidative phosphorylation	See the download page for the video lecture
Friday 16.12.2022 10.15 a.m.	Melle	Seminar Discussion of questions concerning the topics of week #9	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 10 Unit 23 Video lecture	Mrowka	Signal transduction I Principles G-proteins GPCRs Adenylate cyclase, phosphodiesterases	See the download page for the video lecture
Unit 24 Video lecture	Mrowka	Signal transduction II Tyrosine kinase based signalling
Unit 25 Video lecture	Mrowka	Signal transduction III Phosphoinositide based signalling
Friday 06.01.2023 10.15 a.m.	Mrowka	Seminar Discussion of questions concerning the topics of week #10
Week 11 Unit 26 Video lecture	Biskup	Membrane Physiology I - Biophysical basics Diffusuion, dynamic equilibrium Osmosis Electrochemical diffusion Active and passive transport processes	See the download page for the lecture video, lecture notes and exercises
Unit 27 Video lecture	Biskup	Membrane Physiology II - Transport phenomena Primary active transport mechanisms: pumps Secondary active transport mechanisms: symporter, antiporter Passive transport mechanisms: pores, ion channels, uniporter	See the download page for the lecture video, lecture notes and exercises
Unit 28 Video lecture	Biskup	Membrane Physiology III - Excitable tissues Resting membrane potential Action potentials of excitable tissues	See the download page for the lecture video, lecture notes and exercises
Friday 13.01.2023 10.15 a.m.	Biskup	Seminar Discussion of questions concerning the topics of week #11
Week 12 Unit 29 Video lecture	Ebersberger	Physiology of neurons Microscopic anatomy of the neuron Conduction	See the download page for the video lecture
Unit 30 Video lecture	Ebersberger	Synaptic transmission, the neuromuscular junction Structure of electrical and chemical synapses Transmitters	See the download page for the video lecture
Unit 31 Video lecture	Ebersberger	Cellular physiology of the skeletal, cardiac and smooth muscle Excitation and contraction of the skeletal muscle (neuromuscular transmission, excitation-contraction coupling) Excitation and contraction of the cardiac muscle Excitation and contraction of the smooth muscle	See the download page for the video lecture
Friday 20.01.2023 10.15 a.m.	Ebersberger	Seminar Discussion of questions concerning the topics of week #12
Week 13 Unit 32	Biskup	Macroscopic anatomy I Overview Bones and bone structure The axial skeleton	See the download page for literature, lecture slides and exercises
Unit 33	Biskup	Macroscopic anatomy II The apendicular skeleton Joints	See the download page for literature, lecture slides and exercises
Unit 34	Biskup	Macroscopic anatomy III Muscles	See the download page for literature, lecture slides and exercises
Unit 35	Biskup	Macroscopic anatomy IV Inner organs	See the download page for literature, lecture slides and exercises
Friday 27.01.2023 10.15 a.m.	Biskup	Seminar Discussion of questions concerning the topics of week #13
Week 14 Unit 36	Schaible	Organization of the nervous system General design of the nervous system Major levels of CNS function	See the download page for the video lecture
Unit 37	Schaible	Autonomic nervous system Physiologic anatomy of the symathetic and parasympathetic nervous system Autonomic reflexes Pharmacology of the autonomic nervous system	See the download page for the video lecture
Friday 03.02.2023 10.15 a.m.	Schaible	Seminar Discussion of questions concerning the topics of week #14
Week 15 Unit 38	Biskup	Cardiac physiology I Introduction to the cardiovascular system Anatomy of the heart The action potential of the working myocardium	See the download page for lecture video, lecture notes and exercises
Unit 39	Biskup	Cardiac physiology II The excitatory and conductive system of the heart Regulation of the cardiac activity by the autonomous nervous system	See the download page for lecture video, lecture notes and exercises
Unit 40	Biskup	Cardiac physiology III Cardiac mechanics Work diagram of the heart	See the download page for lecture video, lecture notes and exercises
Unit 41	Biskup	Cardiac physiology IV The normal electrocardiogram Cardiac arrhythmias	See the download page for lecture video, lecture notes and exercises
Friday 10.02.2023 10.15 a.m.	Biskup	Seminar Discussion of questions concerning the topics of week #15
03.03.2023 10.15 a.m.	Biskup	Additional seminar Review of this semester's topics, discussion of open questions
10.03.2023 10.00 a.m.	Biskup	Exam Time: 10.00 a.m - 12.00 am. Location: Computer Pool - Ernst-Abbe-Platz 8 - 2nd floor - Room 204