Module A1.4 - Human Biology I

Coordinator

Prof. Dr. Christoph Biskup

Lecturers

Biomolecular Photonics Group: Prof. Dr. Christoph Biskup, PD. Dr. Christian Melle
Institute of Physiology I: Prof. Dr. Hans-Georg Schaible, PD Dr. Andrea Ebersberger
Experimental Nephrology Group: Prof. Dr. Ralf Mrowka

Components of the module

Virtual lectures: Please, follow the links on the download page to view the lectures.
Exercise questions for self study.
Seminars: Seminars/tutorials to discuss remaining questions will take place in the lecture hall of the former Institute of Human Genetics. Enter the historic courtyard of the Medical Theoretical Institutes to get access to the lecture hall. A detailed map can be found here.

Additional help

To help you in learning Human Biology the following tools can be borrowed/obtained:

Molecular models: A set of color coded atoms such as the one used in the lecture videos can be borrowed from the Biomeolecular Photonics group.
Virtual microscopy: Login and pwd for the virtual microscope of the Dept. of Anatomy (link).

Requirements to complete this module

Self study of the recommended textbook chapters. For this course we will use OpenStax Anatomy & Physiology (2017). The textbook is available free of charge at https://openstax.org/details/books/anatomy-and-physiology. A pdf of the book can be downloaded here.
Self study of the online lectures
Regular work on the exercises
Successful participation in the written exam

Exam

Please note: date, time and location might be still subject to changes.

Date: 25.03.2022
Time: 10.00 a.m. - 12.00 a.m.
Location: Big lecture hall of the theoretical medical institutes

Registration

For this course no registration via Friedolin is necessary. For the exam registration via DOSIS within the first 10 weeks after the start of the lecture period is necessary. You will get a note via e-mail when the DOSIS portal is open.

Time table and overview of the individual lectures

nit	Lecturer	Subject and content	Links
Week 1 Monday 18.10.2021 10.15 a.m. Unit 1	Biskup	Zoom meeting Introduction into Human Biology History Principles Aims of this module, how to survive this module	Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 See the download page for a copy of the lecture slides
Tuesday 19.10.2021 10.15 a.m. Unit 2	Biskup	Zoom meeting Introduction into medical terminology	Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3 See the download page for additional materials
Friday 22.10.2021 10.15 a.m Unit 3	Biskup	Seminar - Organization of the cell Cell morphology Physical structure of the cell Functional organization of the cell: cytoplasm, nucleus, organelles	The seminar takes place in the lecture hall of the former Institute of Human Genetics See the download page for additional materials
Week 2 Unit 4	Biskup	Microscopic anatomy Introduction to microscopy Processing and staining of microscopic samples	See the download page for course materials
Unit 5	Biskup	Morphology and classification of tissues Epithelial tissue Connective tissue Muscle tissue Nervous tissue	See the download page for course materials
Unit 6	Biskup	The integumentary sytem Cutaneous membranes: epidermis, dermis Accessory structures: Hair follicles, sebaceous glands, sweat glands, nail	See the download page for course materials
Friday 29.10.2021 10.15 a.m.	Biskup	Seminar Discussion of questions concerning the topics of week #2 The virtual microscope of the Dept. of Anatomy (link)	The seminar takes place in the lecture hall of the former Institute of Human Genetics. To prepare for the seminar, please, work through the material of unit #4-#6 which is available on the download page.
Week 3 Unit 7	Biskup	Biomolecules I Proteinogenic amino acids Properties of amino acids "nonstandard" amino acids Protein folding and protein structure See also the Chemistry Precourse for more details	See the download page for a video lecture
Unit 8	Biskup	Biomolecules II Lipids See the Chemistry Precourse for more details.	See the download page for slides and review questions
Friday 05.11.2021 10.15 a.m.	Biskup	Seminar Discussion of questions concerning the topics of week #3	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 4 Unit 9	Biskup	Biomolecules III Carbohydrates See the Chemistry Precourse for more details.	See the download page for slides and review questions
Unit 10	Biskup	Biomolecules IV Nucleic acids, nucleotides, DNA Forces stabilizing the nucleic acid structure DNA replication	See the download page for slides and review questions
Friday 12.11.2021 10.15 a.m.	Biskup	Seminar Discussion of questions concerning the topics of week #4	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 5 Unit 11	Melle	Chromosome structure	See the download page for a video lecture
Unit 12	Melle	DNA replication	See the download page for a video lecture
Unit 13	Melle	Cell cycle, cell reproduction Cell growth, cell differentiation Cell cycle Cell reproduction Apoptosis	See the download page for a video lecture
Friday 19.11.2021 10.15 a.m.	Melle	Seminar Discussion of questions concerning the topics of week #5	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 6 Unit 14	Melle	Mitosis, meiosis, recombination	See the download page for a video lecture
Unit 15	Melle	Transcription & translation Transcription Translation Regulation of gene expression	See the download page for a video lecture
Friday 26.11.2021 10.15 a.m.	Melle	Zoom meeting Discussion of questions concerning the topics of week #6	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 7 Unit 16	Melle	DNA damage DNA damage signalling DNA repair	See the download page for a video lecture
Unit 17	Mrowka	Molecular cloning recombinant DNA technology chromatographic separations, electrophoresis	See the download page for a video lecture
Friday 03.12.2021 10.15 a.m.	Melle/ Mrowka	Seminar Discussion of questions concerning the topics of week #7	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 8 Unit 18	Biskup	Thermodynamic principles Application of the laws of thermodynamics to biochemistry Gibbs free energy, chemical equilibria Enzyme kinetics	See the download page for slides
Unit 19	Biskup	Enzymes, enzyme kinetics Classification of enzymes Coenzymes Enzyme kinetics, regulation of enzymatic activity	See the download page for slides
Unit 20	Melle	Metabolism I Glycolysis Glykogen metabolism	See the download page for a video lecture
Friday 10.12.2020 10.15 a.m.	Biskup/ Melle	Seminar Discussion of questions concerning the topics of week #8	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 9 Unit 21	Melle	Metabolism II Citric acid cycle	See the download page for a video lecture
Unit 22	Melle	Metabolism III Oxidative phosphorylation	See the download page for a video lecture
Friday 17.12.2020 10.15 a.m.	Melle	Seminar Discussion of questions concerning the topics of week #9	The seminar takes place in the lecture hall of the former Institute of Human Genetics.
Week 10 Unit 23	Mrowka	Signal transduction I Principles G-proteins GPCRs Adenylate cyclase, phosphodiesterases	See the download page for a video lecture
Unit 24	Mrowka	Signal transduction II Tyrosine kinase based signalling
Unit 25	Mrowka	Signal transduction III Phosphoinositide based signalling
Friday 07.01.2022 10.30 a.m.	Mrowka	Seminar Discussion of questions concerning the topics of week #10	Please, note: This seminar will be organized online via zoom. Use the following link to login: https://uni-jena-de.zoom.us/j/66917050911 The passcode is: 642767.
Week 11 Unit 26	Biskup	Membrane Physiology I - Biophysical basics Diffusuion, dynamic equilibrium Osmosis Electrochemical diffusion Active and passive transport processes	See the download page for lecture video, lecture notes and exercises
Unit 27	Biskup	Membrane Physiology II - Transport phenomena Primary active transport mechanisms: pumps Secondary active transport mechanisms: symporter, antiporter Passive transport mechanisms: pores, ion channels, uniporter	See the download page for lecture video, lecture notes and exercises
Unit 28	Biskup	Membrane Physiology III - Excitable tissues Resting membrane potential Action potentials of excitable tissues	See the download page for lecture video, lecture notes and exercises
Friday 14.01.2022 10.30 a.m.	Biskup	Zoom meeting Discussion of questions concerning the topics of week #11	Please, note: Due to corona pandemic regulations all lectures and seminars need to be held online. Use the following link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3
Week 12 Unit 29	Ebersberger	Physiology of neurons Microscopic anatomy of the neuron Conduction	See the download page for a video lecture
Unit 30	Ebersberger	Synaptic transmission, the neuromuscular junction Structure of electrical and chemical synapses Transmitters	See the download page for a video lecture
Unit 31	Ebersberger	Cellular physiology of the skeletal, cardiac and smooth muscle Excitation and contraction of the skeletal muscle (neuromuscular transmission, excitation-contraction coupling) Excitation and contraction of the cardiac muscle Excitation and contraction of the smooth muscle	See the download page for a video lecture
Friday 21.01.2022 10.15 a.m.	Ebersberger	Seminar Discussion of questions concerning the topics of week #12	Use the following link to join the meeting: https://uni-jena-de.zoom.us/j/69635156657 The passcode is: 340835
Week 13 Unit 32	Biskup	Macroscopic anatomy I Overview Bones and bone structure The axial skeleton	See the download page for literature, lecture slides and exercises
Unit 33	Biskup	Macroscopic anatomy II The apendicular skeleton Joints	See the download page for literature, lecture slides and exercises
Unit 34	Biskup	Macroscopic anatomy III Muscles	See the download page for literature, lecture slides and exercises
Unit 35	Biskup	Macroscopic anatomy IV Inner organs	See the download page for literature, lecture slides and exercises
Friday 28.01.2022 10.15 a.m.	Biskup	Seminar Discussion of questions concerning the topics of week #13	Use the following link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3
Week 14 Unit 36	Schaible	Organization of the nervous system General design of the nervous system Major levels of CNS function	See the download page for a video lecture
Unit 37	Schaible	Autonomic nervous system Physiologic anatomy of the symathetic and parasympathetic nervous system Autonomic reflexes Pharmacology of the autonomic nervous system	See the download page for links to video lectures
Friday 04.02.2022 10.15 a.m.	Schaible	Seminar Discussion of questions concerning the topics of week #14	Use the following link to join the meeting: https://uni-jena-de.zoom.us/j/65103228589 The passcode is: 269676
Week 15 Unit 38	Biskup	Cardiac physiology I Introduction to the cardiovascular system Anatomy of the heart The action potential of the working myocardium	See the download page for lecture video, lecture notes and exercises
Unit 39	Biskup	Cardiac physiology II The excitatory and conductive system of the heart Regulation of the cardiac activity by the autonomous nervous system	See the download page for lecture video, lecture notes and exercises
Unit 40	Biskup	Cardiac physiology III Cardiac mechanics Work diagram of the heart	See the download page for lecture video, lecture notes and exercises
Unit 41	Biskup	Cardiac physiology IV The normal electrocardiogram Cardiac arrhythmias	See the download page for recommended videos and exercises
Friday 11.02.2022 10.15 a.m.	Biskup	Seminar Discussion of questions concerning the topics of week #15	Use the following link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3
Friday 18.03.2022 10.15 a.m.	Biskup	Additional zoom meeting Review of this semester's topics, discussion of open questions	Link to join the meeting: https://uni-jena-de.zoom.us/j/4128807326 The passcode is: 9PLFY3
Friday 25.03.2022 10.00-12.00	Biskup	Exam Time: 10.00 a.m - 12.00 am. Location: Big lecture hall of the Medical Theoretical Institutes. Results of the exam can be found here.