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Principal Investigators
Principal Investigators
Prof. Dr. Andreas Simm - Spokesperson
Clinic for Heart and Thoracic Surgery,
MLU Halle-Wittenberg and University Hospital Halle
Ernst-Grube Str. 40
06120 Halle (Saale)
phone: +49 345 5572647
SP8
- Histone glycation, cellular senescence and vascular aging - from molecular mechanism to translation
Prof. Dr. Regine Heller - Deputy Spokesperson
Institute of Molecular Cell Biology - CMB,
Jena University Hospital
Hans-Knöll-Str. 2
07745 Jena
phone: +49 3641 9395633
SP13
- Functional characterization of CML modifications in endothelial cells
Prof. Dr. Rüdiger Horstkorte - Steering Committee Member
Institute for Physiological Chemistry,
MLU Halle-Wittenberg
Hollystr. 1
06114 Halle (Saale)
phone: +49 345 5573873
SP2
- The impact of glycosylation and glycation on the generation and uptake of vehicles in aging cells
Prof. Dr. Lars-Oliver Klotz - Steering Committee Member
Institute of Nutritional Sciences, Nutrigenomics Section,
FSU Jena
Dornburger Straße 29
07743 Jena
phone: +49 3641 949751
SP9
- Age-dependent impact of nitrosative stress-induced changes of mineralocorticoid receptor signaling
Prof. Dr. Stefan H. Heinemann - Steering Committee Member
Department of Biophysics - CMB,
FSU Jena and Jena University Hospital
Hans-Knöll-Str. 2
07745 Jena
phone: +49 3641 9395650
SP12
- Visualization of protein modifications and their impact on the electrical signalling
Prof. Dr. Marcus Glomb
Institute for Chemistry - Food Chemistry,
MLU Halle-Wittenberg
Kurt-Mothes-Str. 2
06120 Halle (Saale)
phone: +49 345 5525784
SP1
- Glutathion modulates glycation
Prof. Dr. Heidi Olzscha
Medical School Hamburg,
University of Applied Sciences and Medical University
Am Kaiserkai 1
20457 Hamburg
phone: +49 361 22643303
SP2
- Acetylation and glycosylation in protein folding and misfolding: Impact on ageing-related diseases
Dr. rer.nat. Astrid Gesper
Institute for Physiological Chemistry,
MLU Halle-Wittenberg
Hollystr. 1
06114 Halle (Saale)
phone: +49 345 5573847
SP2
- The impact of glycosylation and glycation on the generation and uptake of vehicles in aging cells
Dr. rer. nat. Kaya Bork
Institute for Physiological Chemistry,
MLU Halle-Wittenberg
Hollystr.1
06114 Halle (Saale)
phone: +49 345 5573824
SP2
- The impact of glycosylation and glycation on the generation and uptake of vehicles in aging cells
Prof. Dr. Anne Navarrete Santos
Dept. of Anatomy and Cell Biology,
MLU Halle-Wittenberg and University Hospital Halle
Große Steinstrasse 52
06108 Halle (Saale)
phone: +49 345 5571718
SP7
- PTM as molecular mechanism for metabolic memory and ageing of adult stem cells
Prof. Dr. Christian Hübner
Institute of Human Genetics,
Jena University Hospital
Am Klinikum 1
07747 Jena
phone: +49 3641 9396800
SP10
- Glycosylation in the aging brain
Prof. Dr. Claudia Großmann
Julius Bernstein Institute of Physiology,
MLU Halle-Wittenberg
Magdeburger Str. 6
06112 Halle (Saale)
phone: +49 345 5574740
SP11
- Age-dependent impact of nitrosative stress-induced changes of mineralocorticoid receptor signaling
Prof. Dr. Otmar Huber
Institute of Biochemistry II,
Jena University Hospital
Nonnenplan 2-4
07743 Jena
phone: +49 3641 9396400
SP14
- The role of Nit1 in aging-associated stress response
Dr. Alessandro Ori
Leibniz Institute on Aging,
Fritz Lipman Institute
Beutenbergstr. 11
07745 Jena
phone: +49 3641 656808
SP15
- Comprehensive Landscape of Age-induced alterations in protein Ubiquitination and Deubiquitination
Prof. Dr. habil. Thorsten Pfirrmann
Health & Medical University Potsdam
Olympischer Weg 1
14471 Potsdam
phone: +49 331 745113202
SP15
- Comprehensive Landscape of Age-induced alterations in protein Ubiquitination and Deubiquitination
Dr. Matthias Jung
Institute for Physiological Chemistry (IPC),
MLU Halle-Wittenberg
Hollystraße 1
06114 Halle (Saale)
phone: +49 345 557 3839
SP16
- Proteostasis at the old blood-brain barrier: Implications for late-onset Alzheimer’s disease
Prof. Dr. Thomas Hollemann
Institute for Physiological Chemistry (IPC),
MLU Halle-Wittenberg
Hollystrasse 1
06114 Halle (Saale)
phone: +49 345 5573812
SP16
- Proteostasis at the old blood-brain barrier: Implications for late-onset Alzheimer’s disease
Dr. habil. Christoph Kaether
Leibniz Institute on Aging,
Fritz Lipmann Institute
Beutenbergstr. 11
07745 Jena
phone: +49 3641 656230
SP17
- Role of PTMs in senescent-induced transformation of the secretory pathway
Dr. Julia von Maltzahn
Leibniz Institute on Aging,
Fritz Lipmann Institute
Beutenbergstr. 11
07745 Jena
phone: +49 3641 656230
SP18
- Molecular differences underlying functional impairment of aged muscle stem cells
Prof. Dr. Steve Hoffmann
Leibniz Institute on Aging,
Fritz Lipmann Institute
Beutenbergstr. 11
07745 Jena
phone: +49 3641 656810
SP19
- Bioinformatics analysis of transcriptional and epigenomic responses to posttranslational modifications
Dr. Alena van Bömmel
Leibniz Institute on Aging,
Fritz Lipmann Institute
Beutenbergstr. 11
07745 Jena
phone: +49 3641 656810
SP19
- Bioinformatics analysis of transcriptional and epigenomic responses to posttranslational modifications
Jun.-Prof. Dr. Florian Meier-Rosar
Research Group Functional Proteomics,
Jena University Hospital
Am Klinikum 1
07747 Jena
phone: +49 3641 9390879
SP20
- Identification of novel O-GlcNAcylated substrates in endothelial cells and investigation of their role in senescence and ageing
Dr. rer. nat. Daria Zibrova
Institute of Molecular Cell Biology - CMB,
Jena University Hospital
Hans-Knöll-Str. 2
07745 Jena
phone: +49 3642 9395635
SP20
- Identification of novel O-GlcNAcylated substrates in endothelial cells and investigation of their role in senescence and ageing
Dr. rer. nat. Patricia Franzka
Institute of Human Genetics,
Jena University Hospital
Am Klinikum 1
07747 Jena
phone: +49 3641 396882
SP21
- The role of GMPPA in the developing and aging brain
Dr. rer. nat. Sonnhild Mittag
Institute of Biochemistry II,
Jena University Hospital
Nonnenplan 2-4
07743 Jena
phone: +49 3641 9396414
SP21
- The role of GMPPA in the developing and aging brain
Prof. Dr. Andrea Henze
Institute of Agricultural and Nutritional Science,
MLU Halle-Wittenberg
Von-Danckelmann-Platz 2
06120 Halle (Saale)
phone: +49 345 5522702
SP22
- Cross-talk of protein oxidation and protein phosphorylation in insulin secretion