Aktuelle Publikationsliste 2012-2019

begutachtete Originalarbeiten:

Eitner A, Culvenor AG, Wirth W, Schaible HG, Eckstein F. (2020) Impact of Diabetes Mellitus on Knee Osteoarthritis Pain and Physical and Mental Status: Data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2020 Feb 27. doi: 10.1002/acr.24173.

Leuchtweis J, Segond von Banchet G, Eitner A, Ebbinghaus M, Schaible HG. (2020) Pain-related behaviors associated with persistence of mechanical hyperalgesia post antigen-induced arthritis in rats. Pain. 2020 Feb 27. doi: 10.1097/j.pain.0000000000001852.

begutachtete Übersichtsartikel:

Buchbeiträge, Monographien & editorials:

begutachtete Originalarbeiten:

Richter F, Segond von Banchet G, Schaible HG. (2019) Transient Receptor Potential vanilloid 4 ion channel in C-fibres is involved in mechanonociception of the normal and inflamed joint. Sci Rep. 2019 Jul 29;9(1):10928. doi: 10.1038/s41598-019-47342-x.

Ebbinghaus M, Müller S, Segond von Banchet G, Eitner A, Wank I, Hess A, Hilger I, Kamradt T, Schaible HG (2019) The contribution of inflammation and bone destruction to pain in arthritis - a study in murine glucose-6-phosphate isomerase (G6PI)-induced arthritis. Arthritis Rheumatol. 2019 Jul 22. doi: 10.1002/art.41051.

Lehmenkühler A, Richter F (2019) Cortical Spreading Depolarization (CSD) Recorded from Intact Skin, from Surface of Dura Mater or Cortex: Comparison with Intracortical Recordings in the Neocortex of Adult Rats. Neurochem Res. 2019 Feb 1. doi: 10.1007/s11064-019-02737-0.

begutachtete Übersichtsartikel:

Buchbeiträge, Monographien & editorials:

begutachtete Originalarbeiten:

Ebbinghaus M, Jenei-Lanzl Z, Segond von Banchet G, Stangl H, Gajda M, Straub RH, Schaible HG (2018) A Promising New Approach for the Treatment of Inflammatory Pain: Transfer of Stem Cell-Derived Tyrosine Hydroxylase-Positive Cells. Neuroimmunomodulation 2018 Dec 19;25(4):225-237. doi: 10.1159/000495349.

Richter F, Eitner A, Leuchtweis J, Bauer R, Ebersberger A, Lehmenkühler A, Schaible HG (2018) The potential of substance P to initiate and perpetuate cortical spreading depression (CSD) in rat in vivo. Sci Rep. 2018 Dec 5;8(1):17656. doi: 10.1038/s41598-018-36330-2.

begutachtete Übersichtsartikel:

Ebersberger A (2018) The analgesic potential of cytokine neutralization with biologicals. Eur J Pharmacol. doi: 10.1016/j.ejphar.2018.07.040.

Schaible HG (2018) Osteoarthritis pain. Recent advances and controversies. Curr Opin Support Palliat Care 12:148-153.

Schaible HG, Chang HD, Grässel S, Haibel H, Hess A, Kamradt T, Radbruch A, Schett G, Stein C, Straub RH (2018) [Research consortium Neuroimmunology and pain in the research network musculoskeletal diseases]. Z Rheumatol 77:24-30.

Buchbeiträge, Monographien & editorials:

Flor H, Foreman RD, Gebhart GF, Jänig W, Schaible HG (2018) Obituary Prof. Dr. med. D. Sc. h.c. Robert F. Schmidt, Ph.D. Pain 159: 619-620.

Schaible HG, Radbruch L (2018) [Obituary for Prof. Dr. med. D. Sc. h.c. Robert F. Schmidt, Ph.D.]. Schmerz 32:15-16.

Schaible HG, Radbruch L (2018) [A new rubric in Der Schmerz: "PAIN CLINICAL UPDATES"]. Schmerz 32:89.

begutachtete Originalarbeiten:

Ebbinghaus M, Natura G, Segond von Banchet G, Hensellek S, Böttcher M, Hoffmann B, Salah FS, Gajda M, Kamradt T, Schaible HG (2017) Interleukin-17A is involved in mechanical hyperalgesia but not in the severity of murine antigen-induced arthritis. Sci Rep 7:10334.

Eitner A, Pester J, Vogel F, Marintschev I, Lehmann T, Hofmann GO, Schaible HG (2017) Pain sensation in human osteoarthritic knee joints is strongly enhanced by diabetes mellitus. Pain 158:1743-1753.

Richter F, Eitner A, Leuchtweis J, Bauer R, Lehmenkühler A, Schaible HG (2017) Effects of interleukin-1b on cortical spreading depolarization and cerebral vasculature. J Cereb Blood Flow Metab 37:1791-1802.

begutachtete Übersichtsartikel:

Dreier JP et al. (2017) Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group. J Cereb Blood Flow Metab 37:1595-1625.

Eitner A, Hofmann GO, Schaible HG (2017) Mechanisms of Osteoarthritic Pain. Studies in Humans and Experimental Models. Front Mol Neurosci 10:349.

Hartings JA et al. (2017) The continuum of spreading depolarizations in acute cortical lesion development: Examining Leao's legacy. J Cereb Blood Flow Metab 37:1571-1594.

Richter F (2017) Refresher: Physiologie und Pathophysiologie von Fieber. Zeitschrift für Komplementärmedizin 09:46-51.

Buchbeiträge, Monographien & editorials:

Radbruch L, Schaible HG (2017) [Too many pain journals and too few reviewers]. Schmerz 31:405-406.

begutachtete Originalarbeiten:

Boettger MK, Ditze G, Bär KJ, Krüdewagen EM, Schaible HG (2016) Humans, but not animals, perceive the thermal grill illusion as painful. Behav Brain Res 313:172-176.

König C, Morch E, Eitner A, Möller C, Turnquist B, Schaible HG, Ebersberger A (2016) Involvement of Spinal IL-6 Trans-Signaling in the Induction of Hyperexcitability of Deep Dorsal Horn Neurons by Spinal Tumor Necrosis Factor-Alpha. J Neurosci 36:9782-9791.

Richter F, Koulen P, Kaja S (2016) N-Palmitoylethanolamine Prevents the Run-down of Amplitudes in Cortical Spreading Depression Possibly Implicating Proinflammatory Cytokine Release. Sci Rep 6:23481.

Salah FS, Ebbinghaus M, Muley VY, Zhou Z, Al-Saadi KR, Pacyna-Gengelbach M, O'Sullivan GA, Betz H, König R, Wang ZQ, Bräuer R, Petersen I (2016) Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death. Cell Death Dis 7:e2205.

Segond von Banchet G, König C, Patzer J, Eitner A, Leuchtweis J, Ebbinghaus M, Boettger MK, Schaible HG (2016) Long-Lasting Activation of the Transcription Factor CREB in Sensory Neurons by Interleukin-1beta During Antigen-Induced Arthritis in Rats: A Mechanism of Persistent Arthritis Pain? Arthritis Rheumatol 68:532-541.

begutachtete Übersichtsartikel:

Buchbeiträge, Monographien & editorials:

Maihöfner C, Gaul C, Kern KU, Schaible HG, Sommer C (2016) Moderne Praxis der analgetischen Lokaltherapie. UNI-MED Science, UNI-MED-Verlag AG, Bremen, London, Boston

Schaible HG, Radbruch L (2016) [Tracing the neurobiological causes of chronic pain]. Schmerz 30:125-126.

begutachtete Originalarbeiten:

Ebbinghaus M, Segond von Banchet G, Massier J, Gajda M, Bräuer R, Kress M, Schaible HG (2015) Interleukin-6-dependent influence of nociceptive sensory neurons on antigen-induced arthritis. Arthritis Res Ther 17:334.

Jochmann E, Boettger MK, Anand P, Schaible HG (2015) Antigen-induced arthritis in rats is associated with increased growth-associated protein 43-positive intraepidermal nerve fibres remote from the joint. Arthritis Res Ther 17:299.

Massier J, Eitner A, Segond von Banchet G, Schaible HG (2015) Effects of differently activated rodent macrophages on sensory neurons: implications for arthritis pain. Arthritis Rheumatol 67:2263-2272.

begutachtete Übersichtsartikel:

Azad SC, Pogatzki-Zahn EM, Radbruch L, Schaible HG (2015) [Pain medicine yesterday, today, tomorrow: 40 years of the Deutsche Schmerzgesellschaft]. Schmerz 29:466-468.

Casser HR, Schaible HG (2015) [Musculoskeletal pain]. Schmerz 29:486-488, 490-485.

Schaible HG (2015) Are antagonists at bradykinin 1 receptors promising analgesic drugs? Eur J Pain 19:3-4.

Buchbeiträge, Monographien & editorials:

Schaible HG (Editor) (2015) Pain Control. Handb Exp Pharmacol 227, Springer Verlag Berlin, Heidelberg

Schaible HG (2015) Preface. Handb Exp Pharmacol 227:v.

Schaible HG (2015) Emerging concepts of pain therapy based on neuronal mechanisms. Handb Exp Pharmacol 227:1-14.

Schaible HG (2015) Scientific basis of pain. In:Rheumatology (sixth edition), edited by Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, Mosby Ltd., Elsevier, pp. 183-187

Vaupel P, Schaible HG, Mutschler E (2015) Anatomie, Physiologie, Pathophysiologie des Menschen. 7. Auflage, Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart

begutachtete Originalarbeiten:

Ebbinghaus M, Gajda M, Holtzman MJ, Schulz S, Schaible HG (2014) Does chloride channel accessory 3 have a role in arthritis pain? A study on murine antigen-induced arthritis. Neurosci Lett 576:40-44.

König C, Zharsky M, Möller C, Schaible HG, Ebersberger A (2014) Involvement of peripheral and spinal tumor necrosis factor alpha in spinal cord hyperexcitability during knee joint inflammation in rats. Arthritis Rheumatol 66:599-609.

Leuchtweis J, Boettger MK, Niv F, Redecker C, Schaible HG (2014) Enhanced neurogenesis in the hippocampal dentate gyrus during antigen-induced arthritis in adult rat--a crucial role of immunization. PLoS One 9:e89258.

Madishetti S, Schneble N, König C, Hirsch E, Schulz S, Müller JP, Wetzker R (2014) PI3Kgamma integrates cAMP and Akt signalling of the mu-opioid receptor. Br J Pharmacol 171:3328-3337.

Richter F, Lütz W, Eitner A, Leuchtweis J, Lehmenkühler A, Schaible HG (2014) Tumor necrosis factor reduces the amplitude of rat cortical spreading depression in vivo. Ann Neurol 76:43-53.

begutachtete Übersichtsartikel:

Schaible HG (2014) Nociceptive neurons detect cytokines in arthritis. Arthritis Res Ther 16:470.

Schaible HG, Straub RH (2014) Function of the sympathetic supply in acute and chronic experimental joint inflammation. Auton Neurosci 182:55-64.

Buchbeiträge, Monographien & editorials :

Radbruch L, Schaible HG (2014) [Der Schmerz - the leading German-language pain journal]. Schmerz 28:569-570.

Schaible HG, Richter F (2014) Receptors relevant for joint nociception. In: Musculoskeletal Pain: Basic Mechanisms and Implications. edited by Graven-Nielsen T, Arendt-Nielsen L, IASP Press, Washington DC, pp. 187-204

begutachtete Originalarbeiten:

Boettger MK, Krucker S, Gajda M, Schaible HG, Hilberg T (2013) Repeated autologous intraarticular blood injections as an animal model for joint pain in haemophilic arthropathy. Arthritis Res Ther 15:R148.

Dietzel F, Boettger MK, Dahlke K, Holzer J, Lehmann F, Gajda M, Bräuer R, Schaible HG, Kaiser WA, Hilger I (2013) Assessment of rat antigen-induced arthritis and its suppression during glucocorticoid therapy by use of hemicyanine dye probes with different molecular weight in near-infrared fluorescence optical imaging. Invest Radiol 48:729-737.

Eitner A, Pester J, Nietzsche S, Hofmann GO, Schaible HG (2013) The innervation of synovium of human osteoarthritic joints in comparison with normal rat and sheep synovium. Osteoarthritis Cartilage 21:1383-1391.

Leipold E et al. (2013) A de novo gain-of-function mutation in SCN11A causes loss of pain perception. Nat Genet 45:1399-1404.

Natura G, Bär KJ, Eitner A, Boettger MK, Richter F, Hensellek S, Ebersberger A, Leuchtweis J, Maruyama T, Hofmann GO, Halbhuber KJ, Schaible HG (2013) Neuronal prostaglandin E2 receptor subtype EP3 mediates antinociception during inflammation. Proc Natl Acad Sci U S A 110:13648-13653.

Segond von Banchet G, Boettger MK, König C, Iwakura Y, Bräuer R, Schaible HG (2013) Neuronal IL-17 receptor upregulates TRPV4 but not TRPV1 receptors in DRG neurons and mediates mechanical but not thermal hyperalgesia. Mol Cell Neurosci 52:152-160.

begutachtete Übersichtsartikel:

Buchbeiträge, Monographien & editorials :

Radbruch L, Schaible HG (2013) [On the right to have a personal opinion]. Schmerz 27:5-6.

Radbruch L, Schaible HG (2013) [When the pain is gone then you are dead]. Schmerz 27:452-453.

Schaible HG (2013) Naturheilverfahren: Grundlagen Möglichkeiten Grenzen, Physiologische Grundlagen. In: Kursbuch Naturheilverfahren, Volger E, Brinkhaus B (Hrsg). Elsevier, Urban und Fischer, München, pp. 37-44.

Schaible HG (2013) Joint pain: Basic Mechanisms. In Wall and Melzack´s Textbook of Pain, sixth edition, edited by McMahon SB, Tracey I, Koltzenburg M, Turk D, Elsevier Saunders, Philadelphia, PA, pp. 609-619.

Schaible HG, Bräuer R (2013) Acute and chronic arthritis models. In: Pain Models: Translational Relevance and Applications, edited by HO Handwerker and L Arendt-Nielsen, IASP-Press, Washington DC, pp. 149-162.

Schaible H, Straub RH (2013) Pain Neurophysiology. In: Oxford Textbook of Rheumatology, edited by Watts RA, Conaghan PG,  Denton C, Foster H,  Isaacs J, Müller-Ladner U, 4th edition, Oxford University Press, Oxford, UK, pp. 431-436.

begutachtete Originalarbeiten:

Ebbinghaus M, Gajda M, Boettger MK, Schaible HG, Bräuer R (2012) The anti-inflammatory effects of sympathectomy in murine antigen-induced arthritis are associated with a reduction of Th1 and Th17 responses. Ann Rheum Dis 71:253-261.

Ebbinghaus M, Uhlig B, Richter F, von Banchet GS, Gajda M, Bräuer R, Schaible HG (2012) The role of interleukin-1beta in arthritic pain: main involvement in thermal, but not mechanical, hyperalgesia in rat antigen-induced arthritis. Arthritis Rheum 64:3897-3907.

Richter F, Bauer R, Ebersberger A, Lehmenkühler A, Schaible HG (2012) Enhanced neuronal excitability in adult rat brainstem causes widespread repetitive brainstem depolarizations with cardiovascular consequences. J Cereb Blood Flow Metab 32:1535-1545.

Richter F, Natura G, Ebbinghaus M, von Banchet GS, Hensellek S, König C, Bräuer R, Schaible HG (2012) Interleukin-17 sensitizes joint nociceptors to mechanical stimuli and contributes to arthritic pain through neuronal interleukin-17 receptors in rodents. Arthritis Rheum 64:4125-4134.

Vazquez E, Kahlenbach J, Segond von Banchet G, König C, Schaible HG, Ebersberger A (2012) Spinal interleukin-6 is an amplifier of arthritic pain in the rat. Arthritis Rheum 64:2233-2242.

begutachtete Übersichtsartikel:

Schaible HG (2012) [Neuroimmune connections in inflammation and pain. ImmunoPain]. Z Rheumatol 71:698-700.

Schaible HG (2012) Mechanisms of chronic pain in osteoarthritis. Curr Rheumatol Rep 14:549-556.

Buchbeiträge, Monographien & editorials :

Schaible HG (2012) Anatomische, physiologische und pathophysiologische Grundlagen des Schmerzes. In: Chronische Schmerzen in der Praxis - Fragen und Antworten, von Sprott H, Maurer K (Hrsg.), Uni-Med, Bremen, London, Boston, pp. 26-33.

Schaible HG (2012) Physiologie. In: Schmerzmedizin, von Bernateck M, Karst M, Sabatowski R, Siebrecht D (Hrsg.), Thieme, Stuttgart, New York, pp. 21-27