Oncology

The Else Kröner Graduate School AURA - Autophagy - Recycling, Repair, Defense, introduces students of human medicine and dentistry to the topic of autophagy within the framework of a structured qualification program. Within their doctoral projects, the students deal with the mechanisms of autophagy and its regulation as well as with the consequences of impaired autophagy.

• Digitally assisted precision surgery and local therapy – DISSECT - Research focus of the Comprehensive Cancer Center
  To enable radical resection, but also to preserve healthy, functionally important structures and to limit surgical trauma, digitally assisted oncological surgery requires precise pre- and intraoperative visualization. A key element is the intraoperative visualization of tumors using various real time biophotonic techniques, realized by machine learning methods for automated image analysis.

• In the Sensored Surgery project,  an interdisciplinary team is developing a sensor-based support system that can continuously visualize and haptically convey tissue boundaries to surgeons during tumor surgery. The Carl Zeiss Foundation is funding the project through its "CZS Breakthroughs" program.
• The EU -CHARM consortium is working on developing a device that will enable rapid and cost-effective cancer diagnosis based on Raman imaging technologies and artificial intelligence.
• ONCOgenic Receptor Network of Excellence and Training 2.0 
• With the aim of improving and researching therapeutic approaches for tumor treatment, the Automated 3D Tumor-on-Chip Analysis  project aims to establish an immunocompetent 3D skin model for malignant melanoma. This model will be integrated into a microfluidic on-chip application and analyzed online using optical methods.

• German CML Study Group: The German CML Alliance brings together everyone involved in the treatment of chronic myeloid leukemia (CML): treating and research physicians in clinics, practices, and university hospitals, practice and clinic staff, study staff, laboratory diagnosticians, and also the patients themselves.
• in the Else Kröner Research College AntiAge
• in the DFG Clinician Scientist Program OrganAge
• LIVER-T(W)O-HEAL study: Living donor liver transplantation with maximum donor safety in patients with unresectable liver metastases from colorectal cancer 

• FOR 5547: Unraveling the Role of Primary Cilia Dynamics in Tissue Organization and Function.
  Primary cilia are essential for a variety of cellular processes. For example, they play a key role in cell-to-cell communication during tissue and organ development. This communication is crucial to ensuring that tissues are properly organized and function as intended. Defects in this communication can lead to severe developmental disorders and diseases such as cancer.

• Glioma-PerMed – Glioma invasion tests as a predictive tool for personalized glioma medicine

  The development of rapid and efficient glioma invasion assays aims to identify patient-specific, already approved therapeutic agents that can disrupt glioma cell invasion in the clinical setting. 

• The Comprehensive Cancer Center Central Germany unites the two oncology centers in central Germany: the Leipzig University Cancer Center (UCCL) and the UniversityTumorCenter (UTC) Jena.
• Spin-off oncgnostics : Methylation patterns in cervical cancer