Functional analyses of Abp1 - Genetic, cell biological and biochemical examinations in the model organism Drosophila melanogaster show that the correct development of sensory organs, such as eyes and bristles, as well as the proper generation of neuromuscular synapses require actin filament formation mediated by the F-actin binding protein Abp1 at the cell cortex. The project therefore examines the abilities of Abp1 to bind to actin filament, to membranes and to activate the Arp2/3 complex in vitro as well as in the complete organism (Pinyol et al. 2007, Plos ONE; Koch et al. 2012, J. Cell Sci.).