The research activities in the Institute of Molecular Cell Biology are aimed to contribute to the understanding of the complex functioning of signalling proteins. Signalling proteins exhibit relay functions between the molecular components and the complex phenotype of organisms. Using biochemical approaches and techniques of cell biology and physiology, the research groups of the institute investigate molecular reactions of selected signalling proteins in correlation with the concomitant functional pattern of cells and organisms. The exploration of the pathological relevance of signalling reactions is another focus of the institute. Cellular and mice models allow insights into the molecular pathology of selected diseases. The results of these studies contribute to the development of therapeutic concepts against these diseases.