Gieseler-Halbach S, Meltendorf S, Pierau M, Weinert S, Heidel F, Fischer T, Handschuh J, Braun-Dullaeus R, Schrappe M, Lindquist J, Mertens P, Thomas U, Brunner-Weinzierl MC. RSK-mediated nuclear accumulation of the cold shock Y-box protein-1 controls proliferation of T-cells and T-ALL blasts. Cell Death Differ. 2016 Dec 23. doi: 10.1038/cdd.2016.141. [Epub ahead of print]. PMID:28009354
Perner F, Schnöder TM, Fischer T, Heidel FH. Kinomics Screening Identifies Aberrant Phosphorylation of CDC25C in FLT3-ITD-positive AML. Anticancer Res. 2016 Dec;36(12):6249-6258.PMID:27919943
Fischer M, Schnetzke U, Spies-Weisshart B, Walther M, Fleischmann M, Hilgendorf I, Hochhaus A, Scholl S: Impact of FLT3-ITD diversity on response to induction chemotherapy in patients with acute myeloid leukemia. Haematologica. 2016 Dec 29. pii: haematol.2016.157180. doi: 10.3324/haematol.2016.157180. [Epub ahead of print] PMID: 28034991
Winkelmann N, Desole M1, Hilgendorf I, Ernst T, Sayer HG1, Kunert C, Mügge LO, Hochhaus A, Scholl S: Comparison of two dose levels of cyclophosphamide for successful stem cell mobilization in myeloma patients. J Cancer Res Clin Oncol. 2016 Dec;142(12):2603-2610. Epub 2016 Sep 17. PMID: 27640002 DOI:10.1007/s00432-016-2270-9
Karrasch M, Schmidt V, Hammer A, Hochhaus A, Rosée P, Petersen I, Sauerbrei A, Baier M, Sayer HG, Hermann B: Chronic persistent parvovirus B19 bone marrow infection resulting in transfusion-dependent pure red cell aplasia in multiple myeloma after allogeneic haematopoietic stem cell transplantation and severe graft versus host disease. Hematology.2016 Jun 16:1-6.[Epub ahead of print].
PMID:27311084 DOI:10.1080/10245332.2016.1183288
Proschmann R, Baldow C, Rothe T, Suttorp M, Thiede C, Tauer JT, Müller MC, Hochhaus A, Roeder I, Glauche I: Response dynamics of pediatric patients with chronic myeloid leukemia on imatinib therapy. Haematologica. 2016 Nov 17. pii: haematol.2016.154138. [Epub ahead of print]. PMID: 27856510 DOI:10.3324/haematol.2016.154138
Ben Batalla I, Erdmann R, Jørgensen H, Mitchell R, Ernst T, von Amsberg G, Schafhausen P, Velthaus JL, Rankin S, Clark RE, Koschmieder S, Schultze A, Mitra S, Vandenberghe P, Brümmendorf TH, Carmeliet P, Hochhaus A, Pantel K, Bokemeyer C, Helgason GV, Holyoake TL, Loges S: Axl blockade by bgb324 inhibits bcr-abl tyrosine kinase inhibitor-sensitive and -resistant chronic myeloid leukemia. Clin Cancer Res. 2016 Nov 17. pii: clincanres.1930.2016. [Epub ahead of print]
PMID: 27856601, DOI: 10.1158/1078-0432.CCR-16-1930
A. Hochhaus, E. Eigendorff, C. Fabisch, T. Ernst: Chronische myeloische Leukämie – State of the Art. 6 2016 best practice onkologie
Hermann B, Lehners N, Brodhun M, Boden K, Hochhaus A, Kochanek M, Meckel K, Mayer K, Rachow T, Rieger C, Schalk E, Weber T, Schmeier-Jürchott A, Schlattmann P, Teschner D, von Lilienfeld-Toal M: Influenza virus infections in patients with malignancies -- characteristics and outcome of the season 2014/15. A survey conducted by the Infectious Diseases Working Party (AGIHO) of the German Society of Haematology and Medical Oncology (DGHO). Eur J Clin Microbiol Infect Dis. 2016 Nov 12. [Epub ahead of print] doi:10.1007/s10096-016-2833-3. PMID: 27838792
Sieghart Sopper, Satu Mustjoki, Deborah White, Timothy Hughes, Peter Valent, Andreas Burchert, Bjørn T. Gjertsen, Gunther Gastl, Matthias Baldauf, Zlatko Trajanoski, Frank Giles, Andreas Hochhaus, Thomas Ernst, Thomas Schenk, Jeroen J.W.M. Janssen, Gert J. Ossenkoppele, Kimmo Porkka, and Dominik Wolf: Reduced CD62L Expression on T Cells and Increased Soluble CD62L Levels Predict Molecular Response to Tyrosine Kinase Inhibitor Therapy in Early Chronic-Phase Chronic Myelogenous Leukemia. DOI: 10.1200/JCO.2016.67.0893 Journal of Clinical Oncology - published online before print November 7, 2016
Fleischmann M, Schnetzke U, Schrenk KG, Schmidt V, Sayer HG, Hilgendorf I, Hochhaus A, Scholl S: Outcome of FLT3-ITD-positive acute myeloid leukemia: impact of allogeneic stem cell transplantation and tyrosine kinase inhibitor treatment. J Cancer Res Clin Oncol. 2016 Oct 24. [Epub ahead of print] PMID: 27778197
Al-Batran SE, Hofheinz RD, Pauligk C, Kopp HG, Haag GM, Luley KB, Meiler J, Homann N, Lorenzen S, Schmalenberg H, Probst S, Koenigsmann M, Egger M, Prasnikar N, Caca K, Trojan J, Martens UM, Block A, Fischbach W, Mahlberg R, Clemens M, Illerhaus G, Zirlik K, Behringer DM, Schmiegel W, Pohl M, Heike M, Ronellenfitsch U, Schuler M, Bechstein WO, Königsrainer A, Gaiser T, Schirmacher P, Hozaeel W, Reichart A, Goetze TO, Sievert M, Jäger E, Mönig S, Tannapfel A: Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): results from the phase 2 part of a multicentre, open-label, randomised phase 2/3 trial. Lancet Oncol. 2016 Oct 21. pii: S1470-2045(16)30531-9. doi: 10.1016/S1470-2045(16)30531-9. [Epub ahead of print]. PMID: 27776843
Schlenk RF, Stegelmann F, Reiter A, Jost E, Gattermann N, Hebart H, Waller C, Hochhaus A, Platzbecker U, Schafhausen P, Blau IW, Verbeek W, Heidel FH, Werner M, Kreipe H, Teleanu V, Benner A, Döhner H, Grießhammer M, Döhner K: Pomalidomide in myeloproliferative neoplasm-associated myelofibrosis. Leukemia. 2016 Oct 24. doi: 10.1038/leu.2016.299. [Epub ahead of print] PMID:27774990
I. Freitag, C. Beleites, S. Dochow, J. H. Clement, C. Krafft and J. Popp: Recognition of tumor cells by immuno-SERSmarkers in a microfluidic chip at continuous flow. Analyst, DOI: 10.1039/c6an01739h
Hoffmann VS, Baccarani M, Hasford J, Castagnetti F, Di Raimondo F, Casado LF, Turkina A, Zackova D, Ossenkoppele G, Zaritskey A, Höglund M, Simonsson B, Indrak K, Sninska Z, Sacha T, Clark R, Bogdanovic A, Hellmann A, Griskevicius L, Schubert-Fritschle G, Sertic D, Guilhot J, Lejniece S, Zupan I, Burgstaller S, Koskenvesa P, Everaus H, Costeas P, Lindoerfer D, Rosti G, Saussele S, Hochhaus A, Hehlmann R: Treatment and outcome of 2904 CML patients from the EUTOS population-based registry. Leukemia. 2016 Sep 23. doi: 10.1038/leu.2016.246. [Epub ahead of print] PMID:27568522
Padula WV, Larson RA, Dusetzina SB, Apperley JF, Hehlmann R, Baccarani M, Eigendorff E, Guilhot J1, Guilhot F, Hehlmann R, Mahon FX, Martinelli G, Mayer J, Müller MC, Niederwieser D, Saussele S, Schiffer CA, Silver RT, Simonsson B, Conti RM: Cost-effectiveness of Tyrosine Kinase Inhibitor Treatment Strategies for Chronic Myeloid Leukemia in Chronic Phase After Generic Entry of Imatinib in the United States. J Natl Cancer Inst. 2016 Mar 4;108(7). pii: djw003. doi: 10.1093/jnci/djw003. Print 2016 Jul. PMID: 26944912
Nils Winkelmann, Max Desole, Inken Hilgendorf, Thomas Ernst, Herbert G. Sayer, Christa Kunert,· Lars‑Olof Mügge, Andreas Hochhaus, Sebastian Scholl: Comparison of two dose levels of cyclophosphamide for successful stem cell mobilization in myeloma patients. J Cancer Res Clin Oncol. DOI 10.1007/s00432-016-2270-9. PMID:27640002
Kripp M, Merx K, Wirtz RM, Gaiser T, Eidt S, Schwaab J, Post S, Wenz F, Hochhaus A, Hofheinz RD, Erben P: Prognostic Impact of mRNA Expression Levels of HER1-4 (ERBB1-4) in Patients with Locally Advanced Rectal Cancer. Gastroenterol Res Pract. 2016;2016:3481578. doi: 10.1155/2016/3481578. Epub 2016 Aug 16. PMID: 27610130
Cross NC, White HE, Ernst T, Welden L, Dietz C, Saglio G, Mahon FX, Wong CC, Zheng D, Wong S, Wang SS, Akiki S, Albano F, Andrikovics H, Anwar J, Balatzenko G, Bendit I, Beveridge J, Boeckx N, Cerveira N, Cheng SM, Colomer D, Czurda S, Daraio F, Dulucq S, Eggen L, El Housni H, Gerrard G, Gniot M, Izzo B, Jacquin D, Janssen JJ, Jeromin S, Jurcek T, Kim DW, Machova-Polakova K, Martinez-Lopez J, McBean M, Mesanovic S, Mitterbauer-Hohendanner G, Mobtaker H, Mozziconacci MJ, Pajič T, Pallisgaard N, Panagiotidis P, Press RD, Qin YZ, Radich J, Sacha T, Touloumenidou T, Waits P, Wilkinson E, Zadro R, Müller MC, Hochhaus A, Branford S: Development and evaluation of a secondary reference panel for BCR-ABL1 quantification on the International Scale. Leukemia. 2016 Sep;30(9):1844-52. DOI:10.1038/leu.2016.90. Epub 2016 Apr 25. PMID:27109508
Varghese J, Holz C, Neuhaus P, Bernardi M, Boehm A, Ganser A, Gore S, Heaney M, Hochhaus A, Hofmann WK, Krug U, Müller-Tidow C, Smith A, Weltermann A, de Witte T, Hehlmann R, Dugas M.: Key Data Elements in Myeloid Leukemia. Stud Health Technol Inform. 2016;228:282-6. PMID:27577388
RP Gale, A Hochhaus and M-J Zhang: What is the (p-) value of the P-value? Leukemia advance online publication, 26 August 2016; doi:10.1038/leu.2016.193
Melanie Kripp, Kirsten Merx, Ralph Markus Wirtz, Timo Gaiser, Sebastian Eidt, Juliana Schwaab, Stefan Post, Frederik Wenz, Andreas Hochhaus, Ralf-Dieter Hofheinz, and Philipp Erben: Prognostic Impact of mRNA Expression Levels of HER1–4 (ERBB1–4) in Patients with Locally Advanced Rectal Cancer. Gastroenterology Research and Practice, Volume 2016, Article ID 3481578, 9 pages, http://dx.doi.org/10.1155/2016/3481578
Enrico Schalk, Florian H. Heidel: Leukemic mastopathy. Int J Hematol DOI 10.1007/s12185-016-1948-8
Huang K, Yang M, Pan Z, Heidel FH, Scherr M, Eder M, Fischer T, Büsche G, Welte K, von Neuhoff N, Ganser A, Li Z: Leukemogenic potency of the novel FLT3-N676K mutant. Ann Hematol. 2016 Apr;95(5):783-91. doi: 10.1007/s00277-016-2616-z. Epub 2016 Feb 19. PMID: 26891877
Uras IZ, Walter GJ, Scheicher R, Bellutti F, Prchal-Murphy M, Tigan AS, Valent P, Heidel FH, Kubicek S, Scholl C, Fröhling S, Sexl V: Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6. Blood. 2016 Jun 9;127(23):2890-902. doi: 10.1182/blood-2015-11-683581. Epub 2016 Apr 20. PMID: 27099147
Caroline Ebert, Florian Perner, Denise Wolleschak, Tina M. Schnöder, Thomas Fischer, and Florian H. Heidel: Expression and function of ABC-transporter protein ABCB1 correlates with inhibitory capacity of Ruxolitinib in vitro and in vivo. Haematologica March 2016 101: e81-e85; doi:10.3324/haematol.2015.136754
Jentsch-Ullrich K, Eberhardt J, Zeremski V, Koehler M, Wolleschak D, Heidel FH: Characteristics and treatment of polycythemia vera patients in clinical practice: a multicenter chart review on 1476 individuals in Germany. J Cancer Res Clin Oncol. 2016 Sep;142(9):2041-9. doi: 10.1007/s00432-016-2209-1. Epub 2016 Jul 18. PMID: 27431664
Thomas Schenk, Paul La Rosée: Hämophagozytische Lymphohistiozytose des Erwachsenen. Dtsch Med Wochenschr 2016; 141: 1141–1143
Dorer DJ, Knickerbocker RK, Baccarani M, Cortes JE, Hochhaus A, Talpaz M, Haluska FG: Impact of dose intensity of ponatinib on selected adverse events: Multivariate analyses from a pooled population of clinical trial patients. Leuk Res. 2016 Jul 22;48:84-91. doi: 10.1016/j.leukres.2016.07.007. PMID: 27505637
S Saußele, J Richter, A Hochhaus and F-X Mahon: The concept of treatment-free remission in chronic myeloid leukemia. Leukemia. 2016 Aug;30(8):1638-47. doi: 10.1038/leu.2016.115. Epub 2016 May 2. PMID:27133824
JL Steegmann, M Baccarani, M Breccia, LF Casado, V García-Gutiérrez, A Hochhaus, D-W Kim, TD Kim, HJ Khoury, P Le Coutre, J Mayer1, D Milojkovic, K Porkka, D Rea, G Rosti, S Saussele, R Hehlmann and RE Clark: European LeukemiaNet recommendations for the management and avoidance of adverse events of treatment in chronic myeloid leukaemia. Leukemia. 2016 Aug;30(8):1648-71. doi: 10.1038/leu.2016.104. Epub 2016 Apr 28. PMID:27121688
Denise Wolleschak and Florian H. Heidel: Chronic myelogenous leukemia evolving after treatment of multiple myeloma. Blood, 7 2016 128: 146. DOI 10.1182/blood-2016-03-706945
Jorge E. Cortes, Giuseppe Saglio, Hagop M. Kantarjian, Michele Baccarani, Jirı Mayer, Concepci´on Boqu´e, Neil P. Shah, Charles Chuah, Luis Casanova, Brigid Bradley-Garelik, George Manos, and Andreas Hochhaus: Final 5-Year Study Results of DASISION: The Dasatinib Versus Imatinib Study in Treatment-Naïve Chronic Myeloid Leukemia Patients Trial. J Clin Oncol. 2016 May 23. pii: JCO648899. [Epub ahead of print]. PMID:27217448
Neil P. Shah, MD, PhD;Philippe Rousselot, MD, PhD; Charles Schiffer, MD; Delphine Rea, MD, PhD; Jorge E. Cortes, MD; Jorge Milone, MD; Hesham Mohamed, MD; Diane Healey, MS;Hagop Kantarjian, MD; Andreas Hochhaus, MD and Giuseppe Saglio, MD: Dasatinib in imatinib-resistant or -intolerant chronic-phase, chronic myeloid leukemia patients: 7-year follow-up of study CA180-034. Am J Hematol. 2016 May 19. doi: 10.1002/ajh.24423. [Epub ahead of print] PMID:27192969 [PubMed - as supplied by publisher]
Tobias Rachow, Sebastian Dornaus, Herbert G. Sayer, Beate Hermann, Andreas Hochhaus & Marie von Lilienfeld-Toal. Case report: false positive elevated serum-galactomannan levels after autologous hematopoietic stem cell transplantation caused by oral nutritional supplements. Clinical Case Reports 2016; 4(5): 505–508 doi: 10.1002/ccr3.516
Vivien Schäfer, Jana Ernst, Jenny Rinke, Nils Winkelmann, James F. Beck, Andreas Hochhaus, Bernd Gruhn, Thomas Ernst: EZH2 mutations and promoter hypermethylation in childhood acute lymphoblastic leukemia. J Cancer Res Clin Oncol. 2016 May 11. [Epub ahead of print] PMID:27169594 [PubMed - as supplied by publisher]
NCP Cross and A Hochhaus: Deep molecular response in chronic myeloid leukemia. Leukemia advance online publication, 13 May 2016; doi:10.1038/ leu.2016.78 PMID:27174492 [PubMed - as supplied by publisher]
C Gräfe, I Slabu, F Wiekhorst, C Bergemann, F von Eggeling, A Hochhaus, L Trahms and J H Clement: Magnetic particle spectroscopy allows precise quantification of nanoparticles after passage through human brain microvascular endothelial cells. Phys. Med. Biol. 61 (2016) 3986–4000 doi:10.1088/0031-9155/61/11/3986
Richter ME, Neugebauer S, Engelmann F, Hagel S, Ludewig K, La Rosée P, Sayer HG, Hochhaus A, von Lilienfeld-Toal M, Bretschneider T, Pausch C, Engel C, Brunkhorst FM, Kiehntopf M: Biomarker candidates for the detection of an infectious etiology of febrile neutropenia. Infection. 2016 Apr;44(2):175-86. doi: 10.1007/s15010-015-0830-6. Epub 2015 Aug 15. PMID:26275448 [PubMed - in process]
N C P Cross, H E White, T Ernst, L Welden, C Dietz, Guseppe Saglio, F-X Mahon, C C Wong, D Zheng, S Wong, S-S Wang, S Akiki, F Albano, H Andrikovics, J Anwar, G Balatzenko, I Bendit, J Beveridge, N Boeckx, N Cerveira, S-M Cheng, D Colomer, S Czurda, F Daraio, S Dulucq, L Eggen, H El Housni, G Gerrard, M Gniot, B Izzo, D Jacquin, J J W M Janssen, S Jeromin, T Jurcek, D-W Kim, K Machova-Polakova, J Martinez-Lopez, M McBean, S Mesanovic, G Mitterbauer-Hohendanner, H Mobtaker, M-J Mozziconacci, T Pajicˇ, N Pallisgaard, P Panagiotidis, R D Press, Y-Z Qin, J Radich, T Sacha, T Touloumenidou, P Waits, E Wilkinson, R Zadro, M C Müller, A Hochhaus, S Branford, Development and evaluation of a secondary reference panel for BCRABL1 quantitation on the International Scale, Leukemia accepted article preview 25 April 2016; doi: 10.1038/leu.2016.90. PMID: 27109508 [PubMed - as supplied by publisher]
Jeffrey H Lipton, Charles Chuah, Agnès Guerci-Bresler, Gianantonio Rosti, David Simpson, Sarit Assouline, Gabriel Etienne, Franck E Nicolini,Philipp le Coutre, Richard E Clark, Leif Stenke, David Andorsky, Vivian Oehler, Stephanie Lustgarten, Victor M Rivera, Timothy Clackson, Frank G Haluska, Michele Baccarani, Jorge E Cortes, François Guilhot, Andreas Hochhaus, Timothy Hughes, Hagop M Kantarjian, Neil P Shah, Moshe Talpaz, Michael W Deininger, for the EPIC investigators*: Ponatinib versus imatinib for newly diagnosed chronic myeloid leukaemia: an international, randomised, open-label, phase 3 trial. Lancet Oncol. 2016 Apr 12. pii: S1470-2045(16)00080-2. doi: 10.1016/S1470-2045(16)00080-2. [Epub ahead of print] Copyright © 2016 Elsevier Ltd. All rights reserved. PMID: 27083332 [PubMed - as supplied by publisher]
Andrés J M Ferreri, Kate Cwynarski, Elisa Pulczynski, Maurilio Ponzoni, Martina Deckert, Letterio S Politi, Valter Torri, Christopher P Fox, Paul La Rosée, Elisabeth Schorb, Achille Ambrosetti, Alexander Roth, Claire Hemmaway, Angela Ferrari, Kim M Linton, Roberta Rudà, Mascha Binder, Tobias Pukrop, Monica Balzarotti, Alberto Fabbri, Peter Johnson, Jette Sønderskov Gørløv, Georg Hess, Jens Panse, Francesco Pisani, Alessandra Tucci, Stephan Stilgenbauer, Bernd Hertenstein, Ulrich Keller, Stefan W Krause, Alessandro Levis, Hans J Schmoll, Franco Cavalli, Jürgen Finke, Michele Reni, Emanuele Zucca, Gerald Illerhaus, for the International Extranodal Lymphoma Study Group (IELSG): Chemoimmunotherapy with methotrexate, cytarabine, thiotepa, and rituximab (MATRix regimen) in patients with primary CNS lymphoma: results of the fi rst randomisation of the International Extranodal Lymphoma Study Group-32 (IELSG32) phase 2 trial. Lancet Haematol 2016 Published Online April 6, 2016 http://dx.doi.org/10.1016/ S2352-3026(16)00036-3
Schmidt V, Prell T, Treschl A, Klink A, Hochhaus A, Sayer HG.: Clinical Management of Posterior Reversible Encephalopathy Syndrome after Allogeneic Hematopoietic Stem Cell Transplantation: A Case Series and Review of the Literature. Acta Haematol. 2016;135(1):1-10. doi: 10.1159/000430489. Epub 2015 Jul 4. PMID: 26159650
Martin E. Richter, Sophie Neugebauer, Falco Engelmann,· Stefan Hagel,·Katrin Ludewig· Paul La Rosée, Herbert G. Sayer, Andreas Hochhaus, Marie von Lilienfeld‑Toal, Tom Bretschneider, Christine Pausch, Christoph Engel, Frank M. Brunkhorst, Michael Kiehntopf: Biomarker candidates for the detection of an infectious etiology of febrile neutropenia. Infection. 2016 Apr;44(2):175-86. doi: 10.1007/s15010-015-0830-6. Epub 2015 Aug 15. PMID: 26275448 [PubMed - in process]
Noortje Thielen, Johan Richter, Matthias Baldauf, Gisela Barbany, Thoas Fioretos,Francis Giles, Bjørn-Tore Gjertsen, Andreas Hochhaus, Gerrit Jan Schuurhuis, Sieghart Sopper, Leif Stenke, Sarah Thunberg, Dominik Wolf, Gert Ossenkoppele, Kimmo Porkka, Jeroen Janssen, and Satu Mustjoki: Leukemic stem cell quantification in newly diagnosed chronic myeloid leukemia patients predicts response to nilotinib therapy. Clin Cancer Res. 2016 Mar 22. pii: clincanres.2791.2015. [Epub ahead of print] PMID: 27006491
Jana Ernst, Vivien Schäfer, Jenny Rinke, Susan Wittig, James F. Beck, Thomas Ernst, Bernd Gruhn: Continuous molecular remission and regression of side effects after discontinuation of salvage therapy with sorafenib and donor lymphocyte infusions in a young patient with relapsed AML. Ann Hematol DOI 10.1007/s00277-016-2637-7. PMID: 26979170
Charles A. Schiffer, MD; Jorge E. Cortes, MD; Andreas Hochhaus, MD; Giuseppe Saglio, MD; Philipp le Coutre, MD; Kimmo Porkka, MD, PhD; Satu Mustjoki, MD, PhD; Hesham Mohamed, MD; and Neil P. Shah, MD, PhD: Lymphocytosis After Treatment With Dasatinib in Chronic Myeloid Leukemia: Effects on Response and Toxicity. DOI: 10.1002/cncr.29933, Received: September 29, 2015; Revised: January 11, 2016; Accepted: January 20, 2016, Published online Month 00, 2016 in Wiley. Online Library (wileyonlinelibrary.com). PMID: 26998677
F. Hunstig, S. Schulz, I. Nieten, U. Froster, C. Boltze, S. Schliemann,·A. Hochhaus, P. La Rosée: A case of Brooke–Spiegler syndrome with a novel mutation in the CYLD gene in a patient with aggressive on‑Hodgkin’s lymphoma. J Cancer Res Clin Oncol (2016) 142:845–848 DOI 10.1007/s00432-015-2079-y. PMID: 26660106 [PubMed - in process]
Ute Kossak-Roth, Susanne Saußele,· Carlo Aul, Thomas Büchner,·Hartmut Döhner,·Martin Dugas, Gerhard Ehninger, Arnold Ganser,·Aristoteles Giagounidis, Nicola Gökbuget, Martin Griesshammer,·Jörg Hasford,·Michael Heuser,·Wolfgang Hiddemann,· Andreas Hochhaus,·Dieter Hoelzer,· Dietger Niederwieser, AndreasReiter, Christoph Röllig, Rüdiger Hehlmann: Entstehung, Entwicklung und Erfolge des Kompetenznetzes Akute und Chronische Leukämien (KNL). Bundesgesundheitsbl DOI 10.1007/s00103-016-2315-x © Springer-Verlag Berlin Heidelberg 2016
Seyedmehdi Shojaee, Lai N Chan, Maike Buchner, Valeria Cazzaniga, Kadriye Nehir Cosgun, Huimin Geng, Yi Hua Qiu, Marcus Dühren von Minden, Thomas Ernst, Andreas Hochhaus, Giovanni Cazzaniga, Ari Melnick, Steven M Kornblau, Thomas G Graeber, Hong Wu, Hassan Jumaa & Markus Müschen: PTEN opposes negative selection and enables oncogenic transformation of pre-B cells. Nat Med. 2016 Mar 14. doi: 10.1038/nm.4062. [Epub ahead of print] PMID: 26974310 [PubMed - as supplied by publisher]
Fischer M, Spies-Weisshart B, Schrenk K, Gruhn B, Wittig S, Glaser A, et al. (2016) Polymorphisms of Dectin-1 and TLR2 Predispose to Invasive Fungal Disease in Patients with Acute Myeloid Leukemia. PLoS ONE 11(3): e0150632. doi:10.1371/journal.pone.0150632. PMID: 26963509 [PubMed - in process]
MB Miranda, M Lauseke, M-P Kraus, U Proetel, B Hanfstein, A Fabarius, GM Baerlocher, D Heim, DK Hossfeld, H-J Kolb, SW Krause, C Nerl, TH Brümmendorf, W Verbeek, AA Fauser, O Prümmer, K Neben, U Hess, R Mahlberg, C Plöger, M Flasshove, B Rendenbach, W-K Hofmann, MC Müller, M Pfirrmann, A Hochhaus, J Hasford, R Hehlmann and S Saußele: Secondary malignancies in chronic myeloid leukemia patients after imatinib-based treatment: long-term observation in CML Study I. Leukemia (2016), 1–8 © 2016 Macmillan Publishers Limited All rights reserved 0887-6924/16. PMID:26859076
A Hochhaus, T Ernst, S Saußele: Absetzen der Therapie zurzeit nur experimentell. Die Prognose von CML-Patienten hat sich nach Einführung der Tyrosinkinase-Inhibitoren dramatisch verbessert. Bei Erreichen einer tiefen molekularen Remission stellt sich nun die Frage, ob und wann man von einer Heilung sprechen kann. Perspektiven der Onkologie 1/2016 Deutsches Ärzteblatt; DOI: 10.3238/PersOnko/2016.02.12.11. Zum Artikel
A Hochhaus:Therapiekonzepte der chronischen myeloischen Leukämie. TumorDiagn u Ther 2016; 37. Zum Artikel
The European Hematology Association Roadmap for European Hematology Research: a consensus document by Andreas Engert, Carlo Balduini, Anneke Brand, Bertrand Coiffier, Catherine Cordonnier, Hartmut Döhner, Thom Duyvené de Wit, Sabine Eichinger, Willem Fibbe, Tony Green, Fleur de Haas, Achille Iolascon, Thierry Jaffredo, Francesco Rodeghiero, Gilles Salles, Jan Jacob Schuringa, and the other authors of the EHA Roadmap for European Hematology Research. Haematologica. 2016 Feb;101(2):115-208. doi: 10.3324/haematol.2015.136739. Epub 2016 Jan 27. PMID: 26819058 [PubMed - in process
Pfrepper C, Klink A, Behre G, Schenk T, Franke GN, Jentzsch M, Schwind S, Al-Ali HK, Hochhaus A, Niederwieser D, Sayer HG: Risk factors for outcome in refractory acute myeloid leukemia patients treated with a combination of fludarabine, cytarabine, and amsacrine followed by a reduced-intensity conditioning and allogeneic stem cell transplantation. J Cancer Res Clin Oncol. 2016 Jan;142(1):317-24. doi: 10.1007/s00432-015-2050-y. Epub 2015 Sep 30. PMID: 26424692 [PubMed - in process]
Kahl C, Krahl R, Becker C, Al-Ali HK, Sayer HG, Schulze A, Herold M, Hänel M, Scholl S, Hochhaus A, Uharek L, Maschmeyer G, Haehling D, Junghanß C, Peter N, Kämpfe D, Kettner E, Heinicke T, Fischer T, Kreibich U, Wolf HH, Niederwieser D: Long-term follow-up of the AML97 study for patients aged 60 years and above with acute myeloid leukaemia: a study of the East German Haematology and Oncology Study Group (OSHO). J Cancer Res Clin Oncol. 2016 Jan;142(1):305-15. doi: 10.1007/s00432-015-2045-8. Epub 2015 Sep 25. PMID: 26407768 [PubMed - in process]
Usemann J, Ernst T, Schäfer V, Lehmberg K, Seeger K. 2016. EZH2 mutation in an adolescent with Weaver syndrome developing acute myeloid leukemia and secondary hemophagocytic lymphohistiocytosis. Am J Med Genet A. 2016 May;170A(5):1274-7. doi: 10.1002/ajmg.a.37562. Epub 2016 Jan 14. PMID:26762561
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