Engmann Olivia CV

PhD / med. habil. Olivia Engmann

Neuroepigenetics Lab,
Arbeitsgruppenleiterin

Telefon: +49 3641 9-396892
Web

Since 2018	Independent scientist at the Institute for Human Genetics, University Hospital Jena (ongoing: Habilitationsverfahren)
2016 – 2018	Senior postdoctoral fellow in the lab of Isabelle Mansuy, ETH / Universität Zürich, Switzerland
2014 – 2016	Senior postdoctoral fellow in the lab of Eric Nestler, Mount Sinai Hospital, New York, USA
2010 – 2014	Postdoctoral fellow in the lab of Jean-Antoine Girault at INSERM u839, Paris, France
2007 – 2010	PhD in Neuroscience at King’s College London, U.K. (Summa cum Laude)
2007	Diplom in Biology, 1.0 (mit Auszeichnung) from University of Wuerzburg
2006 – 2007	Research intern (“Diplomarbeit”) in the lab of Paul Greengard, The Rockefeller University, New York, USA

Honors and awards (selection)

2017	Seal of Excellence of the European Commission
2017	Delegate of Universität Zürich for the Universitas 21 Workshop on Interculturality and multikulturalism, Santiago, Chile
2016	American Society for Pharmacology and Experimental Therapeutics (ASPET) Award
2009	European College of Neuropsychopharmacology (ECNP) Seminar Award

Past and present sources of funding

IZKF Advanced Medical Research Programm

NARSAD by Brain and Behavioral Research Foundation

Medical Research Council, UK

Boehringer Ingelheim Fonds

Studienstiftung des deutschen Volkes

Teaching

Biologie für Mediziner (1. Semester Medizin und Zahmedizin)

- Vorlesung Teil Zellbiologie

- Praktikum Teil Entwicklung

Neuroepigenetics (Elective module of Master’s Programm Molecular Medicine)

- Lecture 2 SWS Neuroepigenetics

- Seminar 1 SWS Science writing (focus on Neuroepigenetics)

- Practical course 8 SWS

Humangenetik (8. Semester Medizin)

- Seminar Teil Neurogenetik mit Dr. Komazusaki und Dr. Norgauer

Certificates programmes on teaching and leadership

- Media in teaching (LehreLernen, FSU Jena)

- Certificate Basic (LehreLernen, FSU Jena, ongoing)

- Leadership skills (UKJ)

- Fundamentals of Business Administration (Graduate Academy, FSU Jena)

- FELASA-C Course for supervising animal license applications (TU Munich, scheduled for November 2019)

Publications

2019	Labonté B, Jeong YH, Parise E, Issler O, Fatma M, Engmann O, Cho KA, Neve R, Nestler EJ, Koo JW. (2019) Gadd45b mediates depressive-like role through DNA demethylation. Sci Rep 9:4615.
2018	Marion-Poll L, Besnard A, Longueville S, Valjent E, Engmann O, Hervé D, Girault JA (2018) Cocaine conditioned place preference: unexpected effects of testing combined with strong conditioning conditions. Addiction Biology 24:364-75.
	Kremer EA, Gaur N, Lee MA, Engmann O, Bohacek J, Mansuy IM (2018) Novel interplay between TET proteins and microRNAs in the adult brain for memory formation. Scientific Reports 8: 1678.
2017	Labonté B, Engmann O, Purushothaman I, Hodes G, Lorsch Z, Hamilton PJ, Calipari E, Scarpa JR, Loh WHE, Issler O, Kronman H, Walker D, Pfau M, Doyle M, Neve R, Russo S, Kazarskis A, Tamminga C, Mechawar N, Turecki G, Zhang B, Shen L, Nestler EJ (2017) Sex-Specific Transcriptional Signatures in Human Depression. Nature medicine 23: 1102-1111.
	Engmann O, Labonté B, Mitchell A, Bashtrykov P, Calipari ES, Rosenbluh C, Loh EDW, Walker DM, Burek D, Hamilton P, Issler O, Neve R, Turecki G, Hurd Y, Li S, Chess A, Jeltsch A, Akbarian S, Nestler EJ (2017) The largest number of cocaine-induced changes in chromatin modifications are associated with increased expression and 3D looping of Auts2. Biological Psychiatry 82: 794-805.
	Feng J, Pena CJ, Purushothaman I, Engmann O, Walker D, Brown AN, Issler O, Doyle M, Harrigan E, Mouzon E, Vialou V, Shen L, Dawlaty MM, Jänisch R, Nestler EJ (2017) Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors. Neuropsychopharmacology 42:1657-1669.
2016	Engmann O, Giralt A, Girault JA (2016) Acute drug-induced spine changes in the nucleus accumbens are dependent on beta-adducin. Neuropharmacology 110:333-42.
2015	Koo JW, Labonté B, Engmann O, Calipari E, Juarez B, Lorsch Z, Walsh J, Friedman A, Han MU, Nestler EJ (2015) Essential role of mesolimbic brain-derived neurotrophic factor in chronic social stress-induced depressive behaviors Biol. Psychiatry. S0006-3223:01045-8.
	Engmann O, Gervasi N, Giralt A, Marion-Poll A, Gasmi L, Filhol O, Picciotto MR, Gilligan D, Greengard P, Nairn AC, Hervé D, Girault, JA (2015) DARPP-32 interaction with adducin: a possible mediator of rapid environmental effects on striatal neurons Nature communications 6:10099.
	Tiwari SS, d'Orange M, Troakes C, Shurovi BN, Engmann O, Noble W, Hortobágyi T, Giese KP (2015) Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer's disease. Mol Brain 8:6.
2014	Sánchez N, Coura R, Engmann O, Marion-Poll L, Longueville S, Hervé D, Andrés ME, Girault JA (2014) Haloperidol-induced Nur77 expression in striatopallidal neurons is under the control of protein phosphatase 1 regulation by DARPP-32. Neuropharmacology 79:559-66.
2011	Radwanska K, Medvedev NI, Pereira GS, Engmann O, Thiede N, Moraes MF, Villers A, Irvine EE, Maunganidze NS, Pyza EM, Ris L, Szymańska M, Lipiński M, Kaczmarek L, Stewart MG, Giese KP (2011) Mechanism for long-term memory formation when synaptic strengthening is impaired. Proc Natl Acad Sci U S A 108:18471-5.
	Engmann O, Hortobágyi T, Pidsley R, Troakes C, Bernstein HG, Kreutz MR, Mill J, Nikolic M, Giese KP (2011) Schizophrenia is associated with dysregulation of a CDK5 activator that regulates synaptic protein expression and cognition. Brain 134:2408-21.
	Engmann O, Hortobágyi T, Thompson AJ, Guadagno J, Troakes C, Soriano S, Al-Sarraj S, Kim Y, Giese KP (2011) Cyclin-dependent kinase 5 activator p25 is generated during memory formation and is reduced at an early stage in Alzheimer's disease. Biol Psychiatry 70:159-68.
	Michels B, Chen YC, Saumweber T, Mishra D, Tanimoto H, Schmid B, Engmann O, Gerber B (2011) Cellular site and molecular mode of synapsin action in associative learning. Learn Mem 18:332-44.
2010	Engmann O, Campbell J, Ward M, Giese KP, Thompson AJ (2010) Comparison of a protein-level and peptide-level labeling strategy for quantitative proteomics of synaptosomes using isobaric tags. J Proteome Res 9:2725-33.
2008	Sung JY, Engmann O, Teylan MA, Nairn AC, Greengard P, Kim Y (2008) WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines. Proc Natl Acad Sci U S A 105:3112-6.

Reviews and books

2018	Engmann O (2018) Dairy cows – an opportunity in the research field of non-genetic inheritance? Environmental Epigenetics. ecollection 2018 Apr
	Bohacek J, Engmann O, Germain PL, Mansuy IM (2018). Proceedings at the forefront of germline-dependent epigenetic inheritance. Environmental Epigenetics ecollection 2018 Apr
2009	Engmann O, Giese KP (2009) Crosstalk between CDK5 and GSK3beta: Implications for Alzheimer's Disease. Front Mol Neurosci. 2:2
	Engmann O & Brancaccio M (in progress) Circadian Clock in Brain Health and Disease. Springer