Results

PUBLICATIONS

UKJ/CAU: Schrenk S, Brodoehl S, Flor S, Frahm C, Gaser C, Abou-Hamdan R, Herbsleb M, Kaleta C, Kattlun F, Müller HJ, Puta C, Radscheidt M, Ruiz-Rizzo AL, Saraei T, Scherag A, Steidten T, Witte OW, Finke K. Impact of an Online Guided Physical Activity Training on Cognition and Gut-Brain Axis Interactions in Older Adults: Protocol of a Randomized Controlled Trial. Frontiers in Aging Neuroscience, 2023 August, doi: 10.3389/fnagi.2023.1254194

UniVie/KI: Brandt A, Kromm F, Hernández-Arriaga A, Martínez Sánchez I, Övül Bozkir H, Staltner R, Baumann A, Camarinha-Silva A, Diaz Heijtz R, Bergheim I. Cognitive Alterations in Old Mice Are Associated with Intestinal Barrier Dysfunction and Induced Toll-like Receptor 2 and 4 Signaling in Different Brain Regions. Cells, 2023 August, https://doi.org/10.3390/cells12172153

UKJ: Martin EM, Rupprecht S, Schrenk S, Kattlun F, Utech I, Radscheidt M, Brodoehl S, Schwab M, Reuken PA, Stallmach A, Habekost T, Finke K. A hypoarousal model of neurological post-COVID syndrome: the relation between mental fatigue, the level of central nervous activation and cognitive processing speed. Journal of Neurology, 2023 June, https://doi.org/10.1007/s00415-023-11819-7

UKJ: Garo-Pascual M, Gaser C, Zhang L, Tohka J, Medina M, Strange BA. Brain structure and phenotypic profile of superagers compared with age-matched older adults: a longitudinal analysis from the Vallecas Project. Lancet Healthy Longev. 2023 July 13, e374–85, https://doi.org/10.1016/S2666-7568(23)00079-X

NUIG: Heinken A, Hertel J, Acharya G, Ravcheev DA, Nyga M, Okpala OE, Hogan M, Magnúsdóttir S, Martinelli F, Nap B, Preciat G, Edirisinghe JN, Henry CS, Fleming RMT, Thiele I. Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine. Nat Biotechnol. 2023 Jan 19. doi: 10.1038/s41587-022-01628-0

UKJ/CAU: Schmidt S, Haase M, Best L, Groth M, Lindner J, Witte OW, Kaleta C, Frahm C. Restoring Age-Related Cognitive Decline through Environmental Enrichment: A Transcriptomic Approach. Cells. 2022 Nov 30; 11(23):3864. dOI: 10.3390/cells11233864

IDIBGI: Del Castillo-Izquierdo Á, Moreno-Navarrete JM, Latorre J, Arnoriaga-Rodríguez M, Ballanti M, Monteleone G, Paoluzi OA, Mingrone G, Puig J, Ramos R, Garre-Olmo J, Jové M, Pamplona R, Portero-Otín M, Sol J, Lefebvre P, Staels B, Federici M, Fernández-Real JM, Mayneris-Perxachs J. DPP9 as a Potential Novel Mediator in Gastrointestinal Virus Infection. Antioxidants (Basel) 2022 Nov 3; 11(11):2177. doi: 10.3390/antiox11112177

UniVie/UKJ: Brandt A, Baumann A, Hernández-Arriaga A, Jung F, Nier A, Staltner R, Rajcic D, Schmeer C, Witte OW, Wessner B, Franzke B, Wagner KH, Camarinha-Silva A, Bergheim I. Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and ‘inflammaging'. Redox Biol. 2022 Dec; 58:102528. doi:10.1016/j.redox.2022.102528. Epub 2022 Oct 31.

ZHAW/UniVie: Montez De Sousa IR, Bergheim I, Brombach C. Beyond the Individual -A Scoping Review and Bibliometric Mapping of Ecological Determinants of Eating Behavior in Older Adults. Public Health Rev. 2022 Aug. doi: 10.3389/phrs.2022.1604967

IDIBGI: Del Castillo-Izquierdo A, Mayneris-Perxachs J, Fernández-Real JM. Bidirectional relationships between the gut microbiome and sexual traits. Am J Physiol Cell Physiol. 2022 May 4. doi: 10.1152/ajpcell.00116.2022. Epub ahead of print. PMID: 35508190.

UKJ/CAU: Ederer ML, Günther M, Best L, Lindner J, Kaleta C, Witte OW, Simon R, Frahm C. Voluntary Wheel Running in Old C57BL/6 Mice Reduces Age-Related Inflammation in the Colon but Not in the Brain. Cells. 2022 Feb 6;11(3):566. doi: 10.3390/cells11030566. PMID: 35159375; PMCID: PMC8834481.

CAU: Forero-Rodríguez LJ, Josephs-Spaulding J, Flor S, Pinzón A, Kaleta C. Parkinson's Disease and the Metal-Microbiome-Gut-Brain Axis: A Systems Toxicology Approach. Antioxidants (Basel). 2021 Dec 28;11(1):71. doi: 10.3390/antiox11010071. PMID: 35052575; PMCID: PMC8773335.

UKJ: Küchenhoff S, Sorg C, Schneider SC, Kohl O, Müller HJ, Napiórkowski N, Menegaux A, Finke K, Ruiz-Rizzo AL. Visual processing speed is linked to functional connectivity between right frontoparietal and visual networks. European Journal of Neuroscience, 2021 March, https://doi.org/10.1111/ejn.15206

UKJ: Demeyere N, Haupt M, Webb SS, Strobel L, Milosevich E, Moore MJ, Wright H, Finke K, Duta M. Introducing the tablet-based Oxford Cognitive Screen-Plus (OCS-Plus) as an assessment tool for subtle cognitive impairments. Scientific Reports. 2021 March, doi: 10.31234/osf.io/b2vgc

UniVie/UKJ: Baumann A, Hernández-Arriaga A, Brandt A, Sánchez V, Nier A, Jung F, Kehm R, Höhn A, Grune T, Frahm C, Witte OW, Camarinha-Silva A, Bergheim I. Microbiota profiling in aging-associated inflammation and liver degeneration. Int J Med Microbiol. 2021 May;311(4):151500. doi: 10.1016/j.ijmm.2021.151500. Epub 2021 Mar 29. PMID: 33813306.

CONFERENCE TALKS

UKJ: Presentation "Interventionen zur Verlangsamung des Altersprozesses: Bedeutung des Darm Mikrobioms" given at UKJ Interkollegialer Austausch zur Mikrobiomforschung 2.0; April 2023 (Christiane Frahm)

UKJ: Presentation "Introduction to the Innovative Training Network (ITN) ‘SmartAge’: Gut microbiota as a target to modify cognitive ageing" given at 8th Beneficial Microbes Conference; March 2021 (Christiane Frahm)

KI: Presentation "Microbiota-gut-brain axis and mental health: new therapeutic opportunities" given at 8th Beneficial Microbes Conference; March 2021 (Rochellys Diaz Heijtz)

IDIBGI: Presentation "The microbiome and cognition domains" given at 9th Beneficial Microbes Conference; November 2022, Amsterdam, Netherlands (José-Manuel Fernández-Real)

POSTER CONTRIBUTIONS

UKJ: Rowena Simon, Julia Lindner, Marie-Luise Ederer, Madlen Haase, Lena Best, Christoph Kaleta, Otto W. Witte, and Christiane Frahm. "Voluntary Wheel Running in Old C57BL/6 Mice Reduces Age-Related Inflammation in the Colon but Not in the Brain"; XVI European Meeting on Glial Cells in Health and Disease, July 2023, Berlin, Germany

UKJ: Raphaëlle Petit, Simon Schrenk, Tannaz Saraei. SmartAge "Gut-Brain-Axis: How does the gut microbiome affect brain functions in aging?"; Jena Microbiome Meeting 2023, May 2023, Jena, Germany

UKJ (ESR11): Tannaz Saraei, Robert Dahnke, Christian Gaser. Combating CovariATe effects (ComCAT) to enhance statistical power in voxel-based morphometry.; OHBM 2022 Glasgow, UK

CAU (ESR12): Flor et al., Unravelling the role of gut-brain metabolic interactions in aging-associated spatial memory decline; FENS Forum 2022; July 2022; Paris, France

KI (ESR6): Martinez Sanchez et al. Expression of PGN sensing molecules in the brain of young and aged C57BL/6 mice; Bordeaux Summer School - ECNP Immuno-NeuroPsychiatry; July 2021; Bordeaux, France

WUR (ESR10): Kirsten Kruger et al. Interrelationship of the MedDiet and neuroinflammatory status in older adults: analysing host-gut microbiota co-metabolism of tryptophan.; ILSI 4th Symposium on “Nutrition for the Ageing Brain”; August 2022; Lisbon, Portugal

NUIG (ESR13): Nap et al., Manual curation of AGORA2 and the metabolic human; COBRA2022 conference; September 2022; Galway, Ireland

NUIG (ESR13): Nap et al., MARS, the pipeline to go from metagenomic reads to microbiome models; COBRA2022 conference; September 2022; Galway, Ireland

NUIG (ESR13): Nap et al., The nutrition algorithm; COBRA2022 conference; September 2022; Galway, Ireland

ZHAW (ESR15): Poster about the methods used to perform the bibliometric mapping of the scoping review; 59th Scientific Congress of the German Nutrition Society; March 2022; online

PRESENTATION TO NON-SCIENTIFIC PUBLIC

UKJ: press releases (22 October 2020 „Gut-brain axis: Targets for improvement of cognition in the elderly”; 10 January 2022 “Machen Ausdauer und Entspannung auch Gehirn und Darm fit?”)

UKJ: Soundcloud podcast on topic “aging” for study participants SmartAge project 5

UniVie: participation in "KinderUni Wien 2022" (university for children), July 2022

UKJ: participation in "Lange Nacht der Wissenschaften 2022" (long night of science), November 2022