Cai D, Su Q, Chen Y, Luo M. Effect of thyroid hormone deficiency on developmental expression of goalpha gene in the brain of neonatal rats by competitive RT-PCR and in situ hybridization histochemistry. Brain Res. 2000; 864, 195-204

Chen Y, Petersen S, Pacyna-Gengelbach M, Pietas A, Petersen I. Identification of a novel homeobox-containing gene, LAGY, which is downregulated in lung cancer. Oncology 2003 64: 450-458

Chen Y, Knösel T, Kristiansen G, Pietas A, Garber ME, Matsuhashi S, Ozaki I, Petersen I. Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis. J Pathol. 2003; 200, 640-646

Difilippantonio S, Chen Y  Pietas A, Schlüns K, Pacyna-Gengelbach M, Deutschmann N, Padilla-Nash HM, Ried T, Petersen I. Gene expression profiles in human non-small and small-cell lung cancers. Eur J Cancer 2003; 39, 1936-1947

Chen Y, Hühn D, Knösel T, Pacyna-Gengelbach M, Deutschmann N, Petersen I. Downregulation of connexin 26 in human lung cancer is related to promoter methylation. Int J Cancer. 2005, 113: 14-21

Knösel T, Emde A, Schlüns K, Chen Y, Jürchott K, Krause M, Dietel M, Petersen I. Immunoprofiles of 11 biomarkers using tissue microarrays identify prognostic subgroups in colorectal cancer. Neoplasia. 2005;7:741-747

Chen Y, Pacyna-Gengelbach M, Deutschmann N, Niesporek S, Petersen I. Homeobox gene HOP has a tumor suppressive activity in human lung cancer. Int J Cancer 2007; 121: 1021-1027

Chen Y, Pacyna-Gengelbach M, Ye F, Knosel T, Lund P, Deutschmann N, Schluns K, Koth W. Sers C, Yasumoto H, Usui T, Petersen I. Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) has potential tumour-suppressive activity in human lung cancer. J Pathol. 2007; 211, 431-418

Chen Y, Gengelbach M, Deutschmann N, Ye F, Petersen I. Bromodeoxyuridine induced differentiation of a human small cell lung cancer cell line is associated with alteration of gene expression. Biochem Biophys Res Commun. 2007; 353, 559-564

Chen Y, Knösel, Ye, F, Pacyna-Gengelbach M, Deutschmann N; Petersen I. Decreased PITX1 homeobox gene expression in human lung cancer. Lung Cancer. 2007: 55, 287-294

Ye F, Chen Y, Knösel T, Schlüns K, Pacyna-Gengelbach M, Deutschmann N, Lai M, Petersen I. Decreased expression of insulin-like growth factor binding protein 7 in human colorectal carcinoma is related to DNA methylation. J Cancer Res Clin Oncol. 2007; 133, 305-314

Chen Y, Cui T, Knösel T, Yang L, Zöller K, Petersen I. IGFBP7 is a p53 target gene inactivated in human lung cancer by DNA hypermethylation. Lung Cancer. 2011; 73, 38-44

Chen Y, Cui T, Yang L, Mireskandari M, Knoesel T, Zhang Q, Pacyna-Gengelbach M, Petersen I.The diagnostic value of cytokeratin 5/6, 14, 17, and 18 expression in human non-small cell lung cancer. Oncology 2011; 80, 333-340

Penzel R, Sers C, Chen Y, Lehmann-Mühlenhoff U, Merkelbach-Bruse S, Jung A, Kirchner T, Büttner R, Kreipe HH, Petersen I, Dietel M, Schirmacher P. EGFR mutation detection in NSCLC--assessment of diagnostic application and recommendations of the German Panel for Mutation Testing in NSCLC.Virchows Arch. 2011; 458, 95-98

Knösel T, Chen Y, Altendorf-Hofmann A, Danielczok C, Freesmeyer M, Settmacher U, Wurst C, Schulz S, Yang LL, Petersen I. High KIT and PDGFRA are associated with shorter patients survival in gastroenteropancreatic neuroendocrine tumors, but mutations are a rare event. J Cancer Res Clin Oncol. 2011; 138, 397-403

Hamidov Z, Altendorf-Hofmann A, Chen Y, Settmacher U, Petersen I, Knösel T. Reduced expression of desmocollin 2 is an independent prognostic biomarker for shorter patients survival in pancreatic ductal adenocarcinoma. J Clin Pathol. 2011; 64, 990-994

Romeike BR, Chen Y, Walter J, Petersen I. Diagnostic utility of IDH1- and p53-mutation analysis in secondary gliosarcoma. Clin Neuropathol. 2011; 30, 231-234

Cui T, Chen Y, Knösel T, Yang L, Zöller K, Galler K, Berndt A, Mihlan M, Zipfel PF, Petersen I. Human complement factor H is a novel diagnostic marker for lung adenocarcinoma. Int J Oncol. 2011; 39, 161-168

Cui T, Chen Y, Yang L, Knösel T, Zöller K, Huber O, Petersen I. DSC3 expression is regulated by p53, and methylation of DSC3 DNA is a prognostic marker in human colorectal cancer. Br J Cancer. 2011; 104:1013-1019

Yang L, Chen Y, Cui T, Knösel T, Zhang Q, Geier C, Katenkamp D, Petersen I. Identification of biomarkers to distinguish clear cell sarcoma from malignant melanoma. Hum Pathol. 2012; 43, 1462-1470

Kohler LH, Mireskandari M, Knösel T, Altendorf-Hofmann A, Kunze A, Schmidt A, Presselt N, Chen Y, Petersen I. FGFR1 expression and gene copy numbers in human lung cancer. Virchows Arch. 2012; 461, 79-57

Knösel T, Chen Y, Hotovy S, Settmacher U, Altendorf-Hofmann A, Petersen I. Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma. Int J Colorectal Dis. 2012; 27, 1391-1399

Cui T, Chen Y, Yang L, Mireskandari M, Knösel T, Zhang Q, Kohler LH, Kunze A, Presselt N, Petersen I. Diagnostic and prognostic impact of desmocollins in human lung cancer. J Clin Pathol. 2012; 65, 1100-1106

Peifer M, Fernández-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, Plenker D, Leenders F, Sun R, Zander T, Menon R, Koker M, Dahmen I, Müller C, Di Cerbo V, Schildhaus HU, Altmüller J, Baessmann I, Becker C, de Wilde B, Vandesompele J, Böhm D, Ansén S, Gabler F, Wilkening I, Heynck S, Heuckmann JM, Lu X, Carter SL, Cibulskis K, Banerji S, Getz G, Park KS, Rauh D, Grütter C, Fischer M, Pasqualucci L, Wright G, Wainer Z, Russell P, Petersen I, Chen Y, Stoelben E, Ludwig C, Schnabel P, Hoffmann H, Muley T, Brockmann M, Engel-Riedel W, Muscarella LA, Fazio VM, Groen H, Timens W, Sietsma H, Thunnissen E, Smit E, Heideman DA, Snijders PJ, Cappuzzo F, Ligorio C, Damiani S, Field J, Solberg S, Brustugun OT, Lund-Iversen M, Sänger J, Clement JH, Soltermann A, Moch H, Weder W, Solomon B, Soria JC, Validire P, Besse B, Brambilla E, Brambilla C, Lantuejoul S, Lorimier P, Schneider PM, Hallek M, Pao W, Meyerson M, Sage J, Shendure J, Schneider R, Büttner R, Wolf J, Nürnberg P, Perner S, Heukamp LC, Brindle PK, Haas S, Thomas RK. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet. 2012; 44, 1104-1110

Cui T, Chen Y, Yang L, Knösel T, Huber O, Pacyna-Gengelbach M, Petersen I. The p53 target gene desmocollin 3 acts as a novel tumor suppressor through inhibiting EGFR/ERK pathway in human lung cancer. Carcinogenesis. 2012; 33, 2326-2333

Hehne S, Schäfer SM, Richter P, Geier C, Chen Y, von Deimling A, Petersen I. Bone marrow biopsies of patients with hematopoietic and lymphoid disorders - epidemiology, chromosomal aberrations and molecular pathology. Pathol Res Pract. 2012; 208, 510-517

Yang L, Chen Y, Cui T, Knösel T, Zhang Q, Albring KF, Huber O, Petersen. Desmoplakin acts as a tumor suppressor by inhibition of the Wnt/β-catenin signaling pathway in human lung cancer. Carcinogenesis. 2012; 33, 1863-1870

Walluks K, Chen Y, Woelfel C, Yang L, Cui T, Seliger C, Geier C, Knösel T, Hauke S, Petersen I. Analysis of COL1A1-PDGFB fusion transcripts in dermatofibrosarcoma protuberans. Pathol Res Pract. 2013; 209, 30-35

Aust N, Schüle S, Altendorf-Hofmann AK, Chen Y, Knösel T, Dirsch O, Settmacher U, Weise A, Mrasek K, Liehr T. Loss of chromosome 4 correlates with better long-term survival and lower relapse rate after R0-resection of colorectal liver metastases. J Cancer Res Clin Oncol. 2013; 139, 1861-11867

Walther BM, Walther I, Chen Y, Petersen I. GNAS1 mutation analysis in gastrointestinal tumors. Folia Histochem Cytobiol. 2014;52, 90-95

Walther I, Walther BM, Chen Y, Petersen I. Analysis of GNAS1 mutations in myxoid soft tissue and bone tumors. Pathol Res Pract. 2014; 210, 1-4

Berndt A, Büttner R, Gühne S, Gleinig A, Richter P, Chen Y, Franz M, Liebmann C. Effects of activated fibroblasts on phenotype modulation, EGFR signalling and cell cycle regulation in OSCC cells. Exp Cell Res. 2014, 322, 402-414

Müller S, Chen Y, Ginter T, Schäfer C, Buchwald M, Schmitz L, Klitzsch J, Schütz A, Haitel A, Schmid K, Moriggl R, Kenner L, Friedrich KH, Haan C, Petersen I, Heinzel T, and Krämer O. SIAH2 antagonizes TYK2-STAT3 signaling in lung carcinoma cells. Oncotarget. 2014; 5, 3184-3196

Rüping K, Altendorf-Hofmann A, Chen Y, Kampmann E, Gibis S, Lindner L, Katenkamp D, Petersen I, Knösel T. High IGF2 and FGFR3 are associated with tumour progression in undifferentiated pleomorphic sarcomas, but EGFR and FGFR3 mutations are a rare event. J Cancer Res Clin Oncol. 2014; 140, 1315-1322

Saaber F, Chen Y, Cui T, Yang L, Mireskandari M, Petersen I. Expression of desmogleins 1-3 and their clinical impacts on human lung cancer. Pathol Res Pract. 2015; 211, 208-13

Beyer K, Altendorf-Hofmann A, Chen Y, Bickel K, Petersen I. KRAS and aneusomy of chromosomes 4, 10 and 12 in colorectal carcinomas. Pathol Res Pract. 2015; 211, 646-651

Steinbach C, Steinbrücker C, Pollok S, Walther K, Clement JH, Chen Y, Petersen I, Cialla-May D, Weber K, Popp J. KRAS mutation screening by chip-based DNA hybridization--a further step towards personalized oncology. Analyst. 2015; 140, 2747-2754

Chen Y, Yang L, Cui T,  Pacyna-Gengelbach M, Petersen I. HOPX is methylated and exerts tumour suppressive function through Ras-induced senescence in human lung cancer. J Pathol. 2015; 235, 397-407

Mittag S, Valenta T, Weiske J, Bloch L, Klingel S, Gradl D, Wetzel F, Chen Y, Petersen I, Basler K, Huber O. A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/β-catenin signalling pathway. Cell Discov. 2016; 2, 15039

Etzel BM, Gerth M, Chen Y, Wünsche E, Facklam T, Beck JF, Guntinas-Lichius O, Petersen I. Mutation analysis of tumor necrosis factor alpha-induced protein 3 gene in Hodgkin lymphoma. Pathol Res Pract. 2017; 213, 256-260

Ma YX, Chen Y, Petersen I. Expression and promoter DNA methylation of MLH1 in colorectal cancer and lung cancer Pathol Res Pract. 2017; 213, 333-338

Ma YX, Chen Y, Pertersen I. Expression and epigenetic regulation of Cystatin B in lung cancer and colorectal cancer. Pathol Res Pract. 2017; 213, 1568-1574

Chen, k. Schnitzler, Y. Ma, M. Nenkov, B. Theis, I. Petersen. The clinical influence of autophagy-associated proteins on human lung cancer. Disease Markers 2017 https://www.hindawi.com/journals/dm/aip/8314963/

Ma Y, Chen Y, Li Y, Grün K, Berndt A, Zhou Z, Petersen I. Cystatin A suppresses tumor cell growth through inhibiting epithelial to mesenchymal transition in human lung cancer. Oncotarget. 2017 Dec 20;9(18):14084-14098.

Li Y, Chen Y, Ma Y, Nenkov M, Haase D, Petersen I. Collagen prolyl hydroxylase 3 has a tumor suppressive activity in human lung cancer. Exp Cell Res. 2018 1;363(1):121-128.

Inhalt

T. Cui, L. Yang, Y. Ma, I. Petersen, Y. Chen. Desmocollin 3 has tumor suppressive activity through inhibition of Akt pathway in colorectal cancer. Exp. Cell Res. 2019 15;378(2):124-130.

Haase D, Cui T, Yang L, Ma Y, Liu H, Theis B, Petersen I, Chen Y. Plakophilin 1 is methylated and has a tumor suppressive activity in human lung cancer. Exp Mol Pathol. 2019 Jun;108:73-79.

Nenkov M, Ma Y, Haase D, Zhou Z, Li Y, Petersen I, Lu G, Chen Y. Growth inhibitory role of the p53 activator SCH 529074 in non‑small cell lung cancer cells expressing mutant p53. Oncol Rep. 2020 Jun;43(6):2073-2082.  

Ma Y, Schröder DC, Nenkov M, Rizwan MN, Abubrig M, Sonnemann J, Murrieta-Coxca JM, Morales-Prieto DM, Westermann M, Gaßler N, Chen Y. Epithelial Membrane Protein 2 Suppresses Non-Small Cell Lung Cancer Cell Growth by Inhibition of MAPK Pathway. Int J Mol Sci. 2021 Mar 14;22(6):2944.

Nenkov M, Ma Y, Gaßler N, Chen Y. Metabolic Reprogramming of Colorectal Cancer Cells and the Microenvironment: Implication for Therapy. Int J Mol Sci. 2021 Jun 10;22(12):6262. doi: 10.3390/ijms22126262.

Ma Y, Nenkov M, Schröder DC, Abubrig M, Gaßler N, Chen Y. Fibulin 2 Is Hypermethylated and Suppresses Tumor Cell Proliferation through Inhibition of Cell Adhesion and Extracellular Matrix Genes in Non-Small Cell Lung Cancer Int. J. Mol. Sci. 2021, 22(21), 11834; https://doi.org/10.3390/ijms222111834

Ma Y, Nenkov M, Chen Y, Press AT, Kaemmerer E, Gassler N. Fatty acid metabolism and acyl-CoA synthetases in the liver-gut axis. World J Hepatol. 2021 Nov 27;13(11):1512-1533. doi: 10.4254/wjh.v13.i11.1512.

Rizwan MN, Ma Y, Nenkov M, Jin L, Schröder DC, Westermann M, Gaßler N, Chen Y. Tumor-derived exosomes: Key players in non-small cell lung cancer metastasis and their implication for targeted therapy.Mol Carcinog. 2021 Dec 12. doi: 10.1002/mc.23378.