The Center for Health Care Research consolidates health services research activities and promotes the interdisciplinary study of health services-related issues. The center also offers a comprehensive list of projects in health care research.
Further research issues
DFG projects
- DFG Research Unit “Synaptic pathology in autoimmune encephalitis” RU 3004 SYNABS
In the interdisciplinary and translational SYNABS research group, neurologists, physiologists, neuroimmunologists, and microscopy experts investigate the disease mechanisms of autoimmune-induced brain inflammation. Their goal is to develop targeted therapeutic approaches for these diseases, which are often accompanied by psychological symptoms. - The Research Unit RU 2625 „Mechanisms of lysosomal Homeostasis“ is an interdisciplinary network of international scientists from Germany and the Netherlands with extensive expertise in the study of lysosomes, autophagy, and lysosomal diseases. The consortium aims to elucidate the molecular mechanisms that maintain lysosomal homeostasis and the adaptive regulatory mechanisms that compensate for lysosomal dysfunction.
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PETN-Trial: Pentaerytrithyltetranitrate for secondary prophylaxis of intrauterine growth restriction
The prospective, randomized, double-blind, placebo-controlled multicenter study tests the effect of the administration of PETN in high-risk pregnancies on the risk of developing malnutrition in the child and the risk of premature birth. -
HRS-AKI: Randomized controlled trial for the treatment of hepatorenal syndrome
Federally funded projects
- In the SMITH – Smart Medical Information Technology for Healthcare network, over 300 employees from medicine, clinical practice, and IT are working to effectively link research and care. Routine healthcare data generated in everyday clinical practice is processed and made available to medical research in a standardized format. Patients benefit from reliable research results, more precise diagnoses, and improved therapies. Against this backdrop, the university hospitals participating in the consortium in Aachen, Bonn, Essen, Halle, Hamburg, Jena, and Leipzig have established sustainable data integration centers (DIZs) .
- FRESCO: Long-Term Therapeutic Transfer of Encapsulated Stool Microbiome for the Treatment of Active Ulcerative Colitis is a randomized, longitudinal, prospective, three-arm, multicenter, double-blind study to determine the safety and efficacy of repeated fecal microbiota transplantation (FMT) or fecal microbiota filtrate transplantation (FMFT) compared to placebo with oral frozen capsules in 174 randomized patients with mild to moderately active ulcerative colitis.
- GENERATE-BOOST is a study of the CONNECT-GENERATE joint project, a national research network for the explanation, categorization and treatment of autoimmune brain inflammations (encephalitis) and related diseases within the German Network for Research on Autoimmune Encephalitis.
- German Center for Mental Health (DZPG) Development Phase with Halle and Magdeburg.
With the DZPG, another health center will be established. With its focus on translational health research, it will ensure that innovative prevention, diagnostic, and therapeutic methods for mental illnesses are developed and quickly translated into mainstream care. Furthermore, the DZPG will develop solutions to unacceptable societal inequalities in the care of people with mental illnesses.
EU projects
- EuroOC - Interdisciplinary training network for advancing Organ-on-a-chip technology in Europe
Organ-on-a-chip systems enable the replication of human organ tissue on a very small scale. They are considered a future alternative to animal models and a technology with great potential for pharmaceutical research and personalized medicine. Since the development of organ-on-a-chip systems requires skills and expertise from various disciplines, the primary goal of the EUROoC network is the interdisciplinary training of young scientists.
Projects supported by foundations
- Die Hermann und Lilly Schilling-Stiftung fördert die Einrichtung einer Forschungsgruppe für translationale Neurowissenschaften an der Klinik für Neurologie des UKJ. Die Gruppe widmet sich der Erforschung sowohl der zellulären Prozesse von immunvermittelten Erkrankungen des Nervensystems als auch neuen Ansätzen in der Diagnostik und Therapie dieser Erkrankungen. Auf die mit der Leitung der Gruppe verbundene Schilling-Professur wurde Prof. Dr. Christian Geis berufen.
