Classification of sepsis patients to four blood genomic endotypes with pathophysiologic and prognostic implications
Brendon Scicluna, PhD
Center for Experimental and Molecular Medicine; Academic Medical Center, Amsterdam, Netherlands
Download printable poster (pdf)
Date:
Wednesday, 14 December 2016, 2:00 pm
Location:
Conference Room of the Institute for Clinical Chemistry and Laboratory Diagnostics (Oval Office), Jena University Hospital, Am Klinikum 1
Continuing education credits LÄK Thuringia: 2 points category A
Brendon Scicluna received his PhD in Medicine from the Academic Medical Center, University of Amsterdam, with a focus on applying systems biology and computational techniques to identifying novel genes influencing the susceptibility to lethal cardiac arrhythmias. Currently, he works as a post-doctorate researcher at the Center for Experimental Molecular Medicine and Department of Clinical Epidemiology, Biostatistics and Bioinformatics of the Academic Medical Center in Amsterdam, where he focusses on big data analysis with a special focus on blood genomic analyses and sepsis, aiming at elucidation of genomic/transcriptomic biomarkers for the molecular diagnosis and risk stratification (MARS project, www.ctmm.nl). Results of these investigations have been published in high impact journals (Scicluna BP et al., AJRCCM 2015; Cheng SC et al. Nature Immunology 2016, van Vught LA et al., AJRCCM 2016) and led to a patent for a novel molecular biomarker for the rapid diagnosis of community-acquired pneumonia.