Publikationen 2014
1: Ricken T, Werner D, Holzhütter HG, König M, Dahmen U, Dirsch O. Modeling
function-perfusion behavior in liver lobules including tissue, blood, glucose,
lactate and glycogen by use of a coupled two-scale PDE-ODE approach. Biomech
Model Mechanobiol. 2015 Jun;14(3):515-36. doi: 10.1007/s10237-014-0619-z. Epub
2014 Sep 19. PubMed PMID: 25236798.
2: Liu A, Wang W, Fang H, Yang Y, Jiang X, Liu S, Hu J, Hu Q, Dahmen U, Dirsch O.
Baicalein protects against polymicrobial sepsis-induced liver injury via
inhibition of inflammation and apoptosis in mice. Eur J Pharmacol. 2015 Feb
5;748:45-53. doi: 10.1016/j.ejphar.2014.12.014. Epub 2014 Dec 20. PubMed PMID:
25533331.
3: Schwen LO, Wei W, Gremse F, Ehling J, Wang L, Dahmen U, Preusser T.
Algorithmically generated rodent hepatic vascular trees in arbitrary detail. J
Theor Biol. 2015 Jan 21;365:289-300. doi: 10.1016/j.jtbi.2014.10.026. Epub 2014
Nov 5. PubMed PMID: 25451523.
4: Wei W, Dirsch O, Mclean AL, Zafarnia S, Schwier M, Dahmen U. Rodent models and
imaging techniques to study liver regeneration. Eur Surg Res.
2015;54(3-4):97-113. doi: 10.1159/000368573. Epub 2014 Nov 12. Review. PubMed
PMID: 25402256.
5: Liu A, Huang L, Fan H, Fang H, Yang Y, Liu S, Hu J, Hu Q, Dirsch O, Dahmen U.
Baicalein pretreatment protects against liver ischemia/reperfusion injury via
inhibition of NF-κB pathway in mice. Int Immunopharmacol. 2015 Jan;24(1):72-9.
doi: 10.1016/j.intimp.2014.11.014. Epub 2014 Nov 22. PubMed PMID: 25479717.
6: Drasdo D, Bode J, Dahmen U, Dirsch O, Dooley S, Gebhardt R, Ghallab A, Godoy
P, Häussinger D, Hammad S, Hoehme S, Holzhütter HG, Klingmüller U, Kuepfer L,
Timmer J, Zerial M, Hengstler JG. The virtual liver: state of the art and future
perspectives. Arch Toxicol. 2014 Dec;88(12):2071-5. doi:
10.1007/s00204-014-1384-6. PubMed PMID: 25331938.
7: Liu A, Fang H, Wei W, Dirsch O, Dahmen U. Ischemic preconditioning protects
against liver ischemia/reperfusion injury via heme oxygenase-1-mediated
autophagy. Crit Care Med. 2014 Dec;42(12):e762-71. doi:
10.1097/CCM.0000000000000659. PubMed PMID: 25402296.
8: Liu A, Fang H, Wei W, Kan C, Xie C, Dahmen U, Dirsch O. G-CSF pretreatment
aggravates LPS-associated microcirculatory dysfunction and acute liver injury
after partial hepatectomy in rats. Histochem Cell Biol. 2014 Dec;142(6):667-76.
doi: 10.1007/s00418-014-1242-x. Epub 2014 Jul 25. PubMed PMID: 25059648.
9: Xie C, Wei W, Zhang T, Dirsch O, Dahmen U. Monitoring of systemic and hepatic
hemodynamic parameters in mice. J Vis Exp. 2014 Oct 4;(92):e51955. doi:
10.3791/51955. PubMed PMID: 25350047; PubMed Central PMCID: PMC4692415.
10: Deng M, Dahmen U, Sun J, Huang H, Sehestedt C, Homeyer A, Schenk A, Dirsch O.
Limited correlation between conventional pathologist and automatic
computer-assisted quantification of hepatic steatosis due to difference between
event-based and surface-based analysis. IEEE J Biomed Health Inform. 2014
Jul;18(4):1473-7. doi: 10.1109/JBHI.2013.2282999. Epub 2013 Nov 5. PubMed PMID:
24235313.
11: Huang H, Deng M, Jin H, Liu A, Dahmen U, Dirsch O. Reduced hepatic arterial
perfusion impairs the recovery from focal hepatic venous outflow obstruction in
liver-resected rats. Transplantation. 2014 May 27;97(10):1009-18. doi:
10.1097/TP.0000000000000089. PubMed PMID: 24770620.
12: Hammad S, Hoehme S, Friebel A, von Recklinghausen I, Othman A, Begher-Tibbe
B, Reif R, Godoy P, Johann T, Vartak A, Golka K, Bucur PO, Vibert E, Marchan R,
Christ B, Dooley S, Meyer C, Ilkavets I, Dahmen U, Dirsch O, Böttger J, Gebhardt
R, Drasdo D, Hengstler JG. Protocols for staining of bile canalicular and
sinusoidal networks of human, mouse and pig livers, three-dimensional
reconstruction and quantification of tissue microarchitecture by image processing
and analysis. Arch Toxicol. 2014 May;88(5):1161-83. doi:
10.1007/s00204-014-1243-5. Epub 2014 Apr 19. PubMed PMID: 24748404; PubMed
Central PMCID: PMC3996365.
13: Hohmann N, Weiwei W, Dahmen U, Dirsch O, Deutsch A, Voss-Böhme A. How does a
single cell know when the liver has reached its correct size? PLoS One. 2014 Apr
1;9(4):e93207. doi: 10.1371/journal.pone.0093207. eCollection 2014. PubMed PMID:
24690888; PubMed Central PMCID: PMC3972176.
14: Meng Z, Ma Z, Zhang E, Kosinska AD, Liu J, Zhang X, Zhou T, Wu J, Dahmen U,
Dirsch O, Yang D, Roggendorf M, Lu M. Novel Woodchuck Hepatitis Virus (WHV)
transgene mouse models show sex-dependent WHV replicative activity and
development of spontaneous immune responses to WHV proteins. J Virol. 2014
Feb;88(3):1573-81. doi: 10.1128/JVI.02086-13. Epub 2013 Nov 20. PubMed PMID:
24257601; PubMed Central PMCID: PMC3911616.
15: Schleicher J, Guthke R, Dahmen U, Dirsch O, Holzhuetter HG, Schuster S. A
theoretical study of lipid accumulation in the liver-implications for
nonalcoholic fatty liver disease. Biochim Biophys Acta. 2014 Jan;1841(1):62-9.
doi: 10.1016/j.bbalip.2013.08.016. Epub 2013 Aug 30. PubMed PMID: 23999488.
16: Zhang H, Wang W, Fang H, Yang Y, Li X, He J, Jiang X, Wang W, Liu S, Hu J,
Liu A, Dahmen U, Dirsch O. GSK-3β inhibition attenuates CLP-induced liver injury
by reducing inflammation and hepatic cell apoptosis. Mediators Inflamm.
2014;2014:629507. doi: 10.1155/2014/629507. Epub 2014 Nov 30. PubMed PMID:
25525303; PubMed Central PMCID: PMC4265684.